SURGICAL MANAGEMENT OF LIP VITILIGO – A REVIEW
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2014, Vol 1, Issue 11
Abstract
Vitiligo is a common, genetic, autoimmune disease in which there is loss of pigment from areas of the skin resulting in irregular white spots or patches. The skin has normal texture. Vitiligo may appear at any age. People with generalized vitiligo are thought to have otherwise healthy immune system except for the specific immune response to the melanocyte. Vitiligo is non-contagious. It is a result of a combination of genetic, immunologic, biochemical and neurogenic factors. The psychological and social effects of vitiligo are well documented. Mucosal vitiligo can occur as a part of generalized vitiligo or as an isolated condition. Lip involvement is a common feature in dark skinned vitiligo patients with a reported incidence to vary between 20 to 50%. Most commonly, vitiligo involves the vermillion and spares the wet labial mucosa. An inverse pattern of involvement also occurs uncommonly. Involvement of only the most lateral part of the lip is also an uncommon presentation. In acrofacial subtype of vitiligo, there is atypical involvement of the lips. Herpes induced isomorphic or Koebnerization can lead to lip vitiligo. Involvement of mucosa is considered to be an indicator of poor prognostic factor. Vitiligo surgery is recommended for selected, resistant vitiligo patches in patients with vitiligo.
Authors and Affiliations
Mariappan N.
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