Surgical Site Infections: Bacteriological Profile and Antibiogram with Special Reference to MRSA in A Tertiary Care Centre in Western Uttar Pradesh
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 8
Abstract
Background: Surgical site infections (SSI) account for around 15% of all nosocomial infections. In the recent years there has been a growing prevalence of Gram negative organisms as a cause of serious infections in many hospitals. In addition irrational use of broad spectrum antibiotics and resulting antimicrobial resistance has further deteriorated the condition in this regard. Aim: The study aimed to identify bacterial etiology of surgical site infections and their antibiogram in an attempt to develop comprehensive treatment protocol. Materials And Methods: The study was conducted in the department of Microbiology, School of Medical Sciences and Research, Sharda Hospital and University, Greater Noida, over a period of one year from January 2014 to December 2014. The pus samples were collected from all postoperative patients with the evidence of surgical site infections. These were cultured on blood agar and MacConkey agar plates. The growing organisms were identified by standard techniques available. Antibiotic sensitivity testing was performed on Mueller Hinton agar using antibiotics from different classes including beta lactams, glycopeptides, aminoglycosides, macrolides and fluoroquinolones. Results: A total of 83 isolates of various organisms were isolated from different samples of pus. The various organisms isolated were Staphylococcus aureus (31.33%), Pseudomonas aeruginosa (28.92%), E.coli (15.66%), Coagulase negative Staphylococcus (6.02%), Enterococcus (2.41%), Klebsiella pneumoniae (4.82%), Proteus mirabilis (3.61%) and Acinetobacter sp. (7.23%). 53.85% isolates of Staphylococcus aureus were found to be methicillin resistant. Vancomycin was the most effective drug for Gram positive organisms and imipenem for the Gram negative organisms. Drugs from other classes were more or less resistant to the isolated organisms. Conclusion: The inappropriate and prolonged use of antibiotics should be avoided as this leads to development of resistant micro organisms which are even more difficult to get rid of.
Authors and Affiliations
Tarana Sarwat, Vichal Rastogi, Mohd. Rashid, Yogesh Chander
Keywords
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