Surgical treatment of patients with disseminated Ewing sarcoma in our clinical experience
Journal Title: Ortopedia Traumatologia Rehabilitacja - Year 2011, Vol 13, Issue 3
Abstract
Background: Survival in advanced Ewing’s sarcoma is unsatisfactory even with combination treatment. This paper tries to evaluate the impact of surgical treatment on treatment results.Material and Methods: We discuss a series of 24 patients aged 6.1-18.9 years with disseminated Ewing’s sarcoma treated in the years 2000-2008. The patients had metastases to the lungs (13 patients), bone (6 patients), or multiple sites (5 patients). The follow-up period ranged from 8 months to 8.5 years. The patients were treated in accordance with the EE99 protocol. 19 out of the 24 patients underwent surgery. Patients with lung metastases underwent resection of both the primary focus (12 children) as well as the lung metastases (6 children) or radiotherapy. Patients with metastases located elsewhere underwent resection of the primary focus and lung metastases, while the remaining metastatic sites were irradiated (7 children). The 6 remaining children received chemotherapy and radiotherapy. Results: Ten of the 19 patients who were operated on are alive. All those patients that were not operated on have died. The length of survival in the whole group has ranged from 8 months to 8.5 years (mean 2.8 years). Mean overall survival among these patients that were operated on is 3.1 years, and among those who had lung metastases at baseline and underwent metastatectomy, the survival rate is 4.3 years. The average survival rate among the non-operated on patients is 1.6 years.Conclusions: Surgery appears to prolong survival among patients with disseminated Ewing’s sarcoma.
Authors and Affiliations
Anna Raciborska , Katarzyna Bilska , Elżbieta Rogowska , Jan Godziński , Wojciech Wożniak
Keywords
Related Articles
- EP ID EP57116
- DOI -
- Views 98
- Downloads 0
The treatment of intertrochanteric fractures of the femur with Endovis nail
SummaryBackground: The incidence of fractures in the trochanteric area has risen with the increasing numbers of elderly persons with osteoporosis. The imperative goals of treatment are early mobilization by means of stab...
Effectiveness of Physiotherapy in the Treatment of Excessive Lateral Pressure Syndrome after Anterior Cruciate Ligament Reconstruction - Preliminary Report
Background. The excessive lateral pressure syndrome is a common complication following anterior cruciate ligament (ACL) reconstruction is. It may lead to premature wear of the articular surfaces of the femur and patella....
Comparison of Parameters of Spinal Curves in the Sagittal Plane Measured by Photogrammetry and Inclinometry
Background. The photogrammetric method and inclinometer-based measurements are commonly employed to assess the anteroposterior curvatures of the spine. These methods are used both in clinical trials and for screening pur...
Similarities and differences between unilateral and bilateral Perthes' disease
Background. The aim of our research was to compare unilateral and bilateral Perthes disease.Material and methods. The study population consisted of 261 patients with unilateral Perthes disease and 50 with bilateral. The...
<br /> Evaluation of satisfaction with surgical treatment for musculoskeletal dysfunction in children with cerebral palsy<br />
SummaryBackgroundThe variety of symptoms in cerebral palsy (CP) points to the advisability of using the term ‘cerebral palsies’ to underline the complex nature of the associated musculoskeletal dysfunctions. The incidenc...