Surveillance of Chikungunya virus activity in some North-eastern states of India
Journal Title: Asian Pacific Journal of Tropical Medicine - Year 2019, Vol 12, Issue 1
Abstract
Objective: To detect the prevalence pattern of Chikungunya virus in three states of Northeast India. Methods: A total of 1 510 samples were collected from different private and government hospitals of Assam, Arunachal Pradesh and Meghalaya. Serum was tested for the presence of IgM antibodies against Chikungunya virus followed by RT-PCR for amplification of Chikungunya E1 gene region using specific primers. Results: Overall, 11.83% (172/1 454) clinical samples were positive by MAC-ELISA and/or RT-PCR assay. Asymptomatic infection was seen in 17.86%. Males were more affected than females and age group 16-30 years was mostly affected. Fever (100.00%) was the primary symptom followed by headache (72.03%) and arthralgia (41.53%). Only 118 Chikungunya positive cases could be traced, of which 25.42% complained about sequelae of infection. In entomological investigation, Aedes aegypti was more predominant (92.10%) than Aedes albopictus (7.90%). No mosquito pools could be incriminated for Chikungunya virus. Conclusions: In this study, Chikungunya was observed to be prevalent in Assam, Arunachal Pradesh and Meghalaya. Though Chikungunya is a self-limiting infection, increasing morbidity by CHIKV infection is affecting social and economic status of individual. Thus, a community empowerment to effectively control mosquito population by employing different mosquito control measures along with personal protection is mandatory to tackle future outbreak of the disease.
Authors and Affiliations
Prafulla Prafulla Dutta
Keywords
Related Articles
- EP ID EP439885
- DOI 10.4103/1995-7645.250340
- Views 80
- Downloads 0
Antibiofilm activity of a-mangostin extracted from Garcinia mangostana L. against Staphylococcus aureus
Objective: To isolate a-mangostin (AMG) from the peels of mangosteen (Garcinia mangostana L.), grown in Vietnam, and to investigate antibiofilm activity of this compound against three Staphylococcus aureus (S. aureus) st...
Seroprevalence of varicella zoster virus in Colombo district, Sri Lanka
Objective: To determine the seroprevalence of varicella zoster virus (VZV) antibodies among the population residing in the Colombo district of Sri Lanka. Methods: A cross-sectional population-based study was conducted wh...
The first laboratory-confirmed SFTS case from the Xinjiang Uygur Autonomous Region importing to Hainan International Tourism Island
Severe fever with thrombocytopenia syndrome (SFTS) is an acute infectious disease caused by a tick-borne phlebovirus, which was reported to be continuously epidemic in Japan, Korea and in 23 provinces of China since 2010...
Evaluation of in vitro and in vivo immunostimulatory activities of poly (lactic-co-glycolic acid) nanoparticles loaded with soluble and autoclaved Leishmania infantum antigens: A novel vaccine candidate against visceral leishmaniasis
Objective: To prepare and characterize poly lactic-co-glycolic acid (PLGA) nanoparticles loaded with soluble leishmanial antigen or autoclaved leishmanial antigen and explore in vitro and in vivo immunogenicity of antige...
In vitro anticancer activity of polysaccharide extracted from red alga Jania rubens against breast and colon cancer cell lines
Objective: To evaluate the potential role of the polysaccharides of the marine algae as an anticancer agent in vitro against colon cancer cell line (CoCa2) and breast cancer (MCF7) cell lines and to measure lactate dehyd...