Survival Prediction for Romanian Patients with Pancreatic Cancer
Journal Title: JURNALUL DE CHIRURGIE [JOURNAL of SURGERY] - Year 2017, Vol 13, Issue 2
Abstract
Pancreatic cancer is one of the most lethal malignancies worldwide and in some of the latest statistics ranks fourth in the total number of deaths related to cancer in patients of both genders. Currently, curative treatment is only possible in cases of resectable disease and during the initial stages. Still, although complete surgical resection is the only potential curative approach of this disease, it can only be performed in 10 to 20% of patients, since most individuals present with advanced disease upon diagnosis. Moreover, in the recent decades the development and improvement of surgical techniques have only improved postoperative mortality, without having any significant impact on the survival, with specialized pancreatic surgery centres reporting mortality below 5%. In this way, in the present study conducted on 188 patients from the “St. Spiridon” Clinical Emergency Hospital Iasi, we were interested in determining the survival rates in pancreatic cancer, as well as looking at the staging criteria for adenocarcinoma of the pancreas that follows the tumor/node/metastasis (TNM) system and the correlations between any of these stages and the overall survival. Weibull distribution was used to estimate the overall survival. Reduced survival in pancreatic cancer was found to be within the limits found in the published literature: 41.7% at 1 year, 8.7% at 3 years and 1.9% at 5 years. Still, no significant correlation was found between any of the disease stages and the overall survival.
Authors and Affiliations
Daniel Timofte, Mihaela Blaj, Florin Petrariu, Lidia Ionescu, Lăcrămioara Ochiuz
Keywords
Related Articles
- EP ID EP288503
- DOI 10.7438/1584-9341-13-2-3
- Views 78
- Downloads 0
Gas Gangrene: Case Presentation and Literature Data
Although a disease with a particularly historical, war-related implication, gas gangrene still retains its importance in pathology through its highly severe prognosis and rapid death in the absence of immediate treatment...
Approach to a Patient with Post Laparoscopic Cholecystectomy Bile Leak
With the widespread practice of laparoscopic cholecystectomy and the advancements in imaging and endoscopic therapy the management of bile leaks following cholecystectomy has evolved over the years. Majority of the bile...
Patent Vitellointestinal Duct with Inverted Ileal Loop Prolapse with Strangulation at Birth in Preterm (34 Weeks): A Rare Presentation
Patent vitellointestinal duct (VID) can present to us in many variety of congenital intestinal malformations. Patient presents with either anomaly alone or complications secondary to the anomaly. Most common reported ano...
Intestinal Malrotation and Appendicitis in Adults
Background: Intestinal malrotation is a rare condition resulting from an incomplete midgut rotation and fixation; most of the cases were diagnosed in the newborn and the presentation at adulthood is traditionally conside...
Fistulas after Low Anterior Resection with TME
Despite advances in modern anastomotic techniques for colorectal surgery, anastomotic fistulas are still considered a dreaded complication, with a reported rate varying from 2 to 25%. Although fistulas can appear after a...