Susceptibility of E. coli to Commonly Used Antimicrobials isolated From Urine Samples
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 7
Abstract
Abstract:Urinary tract infections (UTIs) are among the most common infectious diseases all over the world. Recent studies reported an increased antibiotic resistance in Escherichia coli, primary causative agent of UTI. The resistance has emerged even to more potent antimicrobial agents like fluoroquinolones. Details of 204 urine culture positive reports for E.coli and their antibiotic sensitivity pattern pertaining to the study period of 4 years from Jan 2012 to Dec 2015 were collected from Central Microbiology Laboratory of Tertiary care Hospital and the results were statistically analysed. The sensitivity pattern of E.coli to antibiotics in UTI were Nitrofurantoin (89.68%), Amikacin (88.25%), Co-trimoxazole (27.44%), Gentamycin (49.90%), Ceftazidime (22.5%), Ciprofloxacin (10.78%), Levofloxacin ( 31.85% ) Cefotaxime (15.78%), Cefuroxime (14.21% ), Ceftriaxone (16.17%), Piperacillin-Tazobactum (85.27%). The isolates showed high levels of resistance to Ampicillin, Amoxicillin-Clavulanic Acid, Norfloxacin, Cefuroxime, Ceftriaxone and Co-trimoxazole. The study shows that the organism E.coli in UTI is resistant to commonly prescribed drugs like Quinolones. This resistance was seen more in the in-patients, elderly males and females. The drug Quinolone is commonly prescribed because it achieves high concentration in urine. Over use of Quinolone has led to increased prevalence of E.coli resistance to Quinolones E.coli has developed resistance to third generation Cephalosporins, Quinolones, and cotrimoxazole and so they cannot be considered for empirical treatment in UTI caused by E.coliin this group of population. Keywords:E. coli, Urinary Tract Infection, Antibiotic sensitivity.
Authors and Affiliations
Lakshmi Jyothi T, P Naveen Chandra Reddy, Sai Charan
Keywords
Related Articles
- EP ID EP375040
- DOI -
- Views 34
- Downloads 0
Histopathological Study of Undescended Testis in Pediatric Age Group
After development of the testis in the abdominal cavity, if its descent is arrested anywhere along its normal pathway of migration undescended testis results. Undescended testis is a multifactorial disease as the specifi...
A study of pattern and causes of anemia in elderly patients admitted at tertiary centre
Abstract: Anemia in the elderly is common and increasing as the population ages. In older patients, anemia of any degree contributes significantly to morbidity and mortality and has a significant effect on the quality of...
Plasma Protein Patterns in Pulmonary Tuberculosis Using Protein Electrophoresis
Serum protein was analyzed by electrophoresis and photometric method in sera of adults’ patients with pulmonary tuberculosis and adults healthy individuals. Results were found to be as follows: A) The mean values of the...
An Evaluation of Effect of Flaxseed Oil (N-3 Fatty Acid) Treatment on Lipid Parameters and Its Tolerability in Dyslipidemic Patients
To evaluate the effect of flaxseed oil treatment on lipid parameters and to assess tolerability of the same in dyslipidemic patients. An interventional, prospective study was conducted on outpatients of either gender in...
A study of correlation between the environmental factors and occurrence of Influenza an H1N1cases in Baroda district
The Influenza a H1N1 in humans can be a mild illness or in some people it may result in serious, even life-threatening complications such as pneumonia, acute bronchitis, worsening of chronic conditions, respiratory failu...