Susceptibility of E. coli to Commonly Used Antimicrobials isolated From Urine Samples
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 7
Abstract
Abstract:Urinary tract infections (UTIs) are among the most common infectious diseases all over the world. Recent studies reported an increased antibiotic resistance in Escherichia coli, primary causative agent of UTI. The resistance has emerged even to more potent antimicrobial agents like fluoroquinolones. Details of 204 urine culture positive reports for E.coli and their antibiotic sensitivity pattern pertaining to the study period of 4 years from Jan 2012 to Dec 2015 were collected from Central Microbiology Laboratory of Tertiary care Hospital and the results were statistically analysed. The sensitivity pattern of E.coli to antibiotics in UTI were Nitrofurantoin (89.68%), Amikacin (88.25%), Co-trimoxazole (27.44%), Gentamycin (49.90%), Ceftazidime (22.5%), Ciprofloxacin (10.78%), Levofloxacin ( 31.85% ) Cefotaxime (15.78%), Cefuroxime (14.21% ), Ceftriaxone (16.17%), Piperacillin-Tazobactum (85.27%). The isolates showed high levels of resistance to Ampicillin, Amoxicillin-Clavulanic Acid, Norfloxacin, Cefuroxime, Ceftriaxone and Co-trimoxazole. The study shows that the organism E.coli in UTI is resistant to commonly prescribed drugs like Quinolones. This resistance was seen more in the in-patients, elderly males and females. The drug Quinolone is commonly prescribed because it achieves high concentration in urine. Over use of Quinolone has led to increased prevalence of E.coli resistance to Quinolones E.coli has developed resistance to third generation Cephalosporins, Quinolones, and cotrimoxazole and so they cannot be considered for empirical treatment in UTI caused by E.coliin this group of population. Keywords:E. coli, Urinary Tract Infection, Antibiotic sensitivity.
Authors and Affiliations
Lakshmi Jyothi T, P Naveen Chandra Reddy, Sai Charan
Keywords
Related Articles
- EP ID EP375040
- DOI -
- Views 63
- Downloads 0
Correlation of Adiposity with Fasting Blood Glucose in Young Individuals
India is undergoing rapid epidemiological transition with increased urbanization and socio-economic development. It has resulted in a dramatic change in lifestyles that consist of low physical activity, fat-rich diet, su...
Isolation of Anaerobes in Bacterial Vaginosis
Abstract: Anaerobic bacteria causing Bacterial Vaginosis (BV) have been linked to a wide variety of upper genital tract infections, particularly in child bearing age. The aim of the study is to know the prevalence of ana...
Spectrum of Hereditary Hemolytic Anemia-A Tertiary Care Hospital Based Study
Abstract: Hereditary hemolytic anemias are broad category of hematological disorders that include hemoglobinopathies,enzymopathies and membrane disorders.Though most of the cases are clinically inapparent still hereditar...
Multiple Congenital Anomaly with Dysmorphism and Arthrogryposis: Case report
Arthrogryposis multiplex congenita (AMC), or simply arthrogryposis, describes congenital joint contractures in two or more areas of the body found throughout the body at birth. The name, derived from the Greek, means “cu...
A Controlled Clinical Study on the Role of Nasya Karma and Shirodhara in the Management of Migraine
Migraine (Ardhavbhedaka) is now recognized as a chronic illness, the second most common cause of headache, not simply as a headache. With advent of modern drugs, the pattern of disease has grossly changed, where the drug...