SYNTHESES OF 2-(4'-METHOXY-3'-(R-AMINOSULFONYL)BENZYL]2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-1,3-DIONES
Journal Title: Вчені записки Таврійського національного університету імені В. І. Вернадського. Серія: Технічні науки - Year 2018, Vol 29, Issue 5
Abstract
This paper is devoted to the study of synthetic modifications of naphthalic anhydride by condensation with 4-methoxybenzylamine and further sulfochloration reaction of the product obtained. The resulting sulfonylchloride was used as a starting reagent for the synthesis of previously unknown 2-(4'-methoxy-3'-(R-aminosulfonyl) benzyl]2,3-Dihydro-1H-benzo[de]isoquinoline-1,3-diones. The structure of all the compounds obtained is confirmed by 1H NMR spectra, and the composition by the element analysis data. The results of these studies are used in synthetic practice, and the compounds obtained are promising for further study of their biological activity.
Authors and Affiliations
Н. В. Сімурова, І. В. Попова, Н. Ю. Зінченко, В. М. Брицун
Keywords
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