Synthesis and Antimicrobial Evaluation of Certain Novel Thiazoles
Journal Title: Advanced Pharmaceutical Bulletin - Year 2013, Vol 3, Issue 1
Abstract
Purpose: This article makes an attempt to synthesize certain compounds containing thiazole and imidazole moieties and screen for the antimicrobial properties. Methods: The novel compounds synthesized were characterized by elemental analysis, IR and 1HNMR spectral data. The antimicrobial activity of novel compounds was evaluated by cup plate method. Results: The compound p-t showed more antibacterial activity than that of the standard. p-hp and p-as showed considerable antibacterial activity. p-t demonstrated higher antifungal activity than that of the standard while p-hp and p-as showed considerable antifungal activity. Conclusion: The antimicrobial activity studies were conducted on certain selected bacteria and fungi. In each case antimicrobial activity of the compounds was compared with that of standards. p-t, p-hp, p-np, p-cp, p-ts and p-as showed considerable antimicrobial activity.
Authors and Affiliations
Meesaraganda Sreedevi, Aluru Raghavendra Guru Prasad, Yadati Narasimha Spoorthy, Lakshmana Rao Krishna Rao Ravindranath
Keywords
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- EP ID EP161867
- DOI http://dx.doi.org/10.5681/apb.2013.037
- Views 116
- Downloads 0
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