SYNTHESIS AND CHARACTERIZATION OF NOVEL 1,3-OXAZEPINE DERIVATIVES FROM AMINOPYRAZINE
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2017, Vol 6, Issue 5
Abstract
In this work new 1,3-oxazepine subsidiaries have been readied, by two stages: The initial step incorporate amino gathering of the 2-aminopyrazine was dense with various fragrant aldehydes within the sight of supreme ethanol to give novel Schiff bases subordinates [A1 – A5] separately. The second step, the subsequent imines subordinates [A1-A5] were responded with maleic anhydride and phathalic anhydride in dry toluene to give new 1,3-oxazepine-4,7-dione ring subsidiaries [B1a-B5a] and [B1b-B5b] individually scheme[I]. Every one of these mixes were described by liquefying focuses and FT.IR spectroscopy, several of them were portrayed by 1H-NMR spectroscopy and C.H.N. S. examination.
Authors and Affiliations
Hawraa Mohammed Sadiq
Keywords
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