SYNTHESIS AND CHARACTERIZATION OF SOME ANTIMICROBIAL MANNICH BASES
Journal Title: World Journal of Pharmaceutical and life sciences - Year 2017, Vol 3, Issue 9
Abstract
Three Mannich bases: 2-hydroxymethyl-4-morpholinomethyl-1, 5-diphenyl-pent-1,4-dien-3-one(I); 2-acetamidomethy l-4-acetamidophenol(II) and 1-phenyl-3-(pyrrolidino-1-yl)propan-1-one(III) were synthesized via a general synthesis strategy. They were identified by spectral data (UV, IR, NMR and MS). Mannich bases I and II were evaluated for their antimicrobial potential and promising activity was observed.
Authors and Affiliations
Dr. Abdel Karim M.
Keywords
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