SYNTHESIS AND EVALUATION OF ANTIMICROBIAL ACTIVITY OF 1-BENZOYL-1H-PYRAZOLO [4,3-C]QUINOLIN-4(5H)-ONES
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 1
Abstract
A series of 1-benzoyl-1H-pyrazolo [4,3-C]quinolin-4(5H)-one, carrying appropriate substituents at the Quinoline ring have been synthesized in good yields via the condensation of 4-chloro-3-formylquinolin-2[1H]ones with benzohydrazide using triethylamine as a base. All the synthesized compounds were evaluated for their antibacterial activities.
Authors and Affiliations
Murugesh Shivashankar , Badal Mandal , prakash G Arul
Keywords
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