SYNTHESIS AND EVALUATION OF IODINATED PHENYTOIN FOR ANTIMICROBIAL ACTIVITY
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2014, Vol 5, Issue 3
Abstract
5,5-bis(4'-iodophenyl)imidazolidine-2,4-dione was prepared either by direct iodination of 5,5-diphenyl imidazolidin-2,4-dione (phenytoin) or through the iodination of phenytoin intermediates (benzoin and benzil) and follow-up the standard procedure used for conversion of them to phenytoin. The targeted compound was evaluated and compared with the antimicrobial activity of phenytoin.
Authors and Affiliations
Loay Abdulrahman, Mohammed Mohammed, Mustafa Qasim
Keywords
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