SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF 1,3,4-THIADIAZOLE DERIVATIVES: A REVIEW
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 3
Abstract
1,3,4-Thiadiazole and their derivatives exhibit a broad spectrum of biological effectiveness like antimicrobial, antiinflammatory, antitubercular, antidiabetic, anticancer, antidepressant, anti- parkinson, hypoglycaemic, anti-hypertensive and diuretic activity. This review provide a broad view of chemistry of 1,3,4-thiadiazole system and it includes the literature survey on methods of preparation and pharmacological activities of 1,3,4-thiadiazole moiety. As a result, compounds containing 1,3,4-thiadiazole were attracted much attention in the field of medicines.
Authors and Affiliations
Tanveer Ahmad, Arvind Singh, Nupur Jaiswal, Deepika Singh
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