Synthesis and spectral characterization of esomeprazole sodium Polymorphic form
Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 4
Abstract
Regulatory authorities throughout the world require that all possible crystalline forms of the same active drug compound be synthesized and characterized as completely as possible. There is thus a continuing need to prepare new polymorphic forms of pharmacologically active compounds. Therefore it is need for preparation of highly pure polymorphic form N esomeprazole sodium by a repeatable process which guarantees stable physical form. Despite the fact that there are numerous known forms of omeprazole, the need continues to exist for novel, pharmaceutically-acceptable forms of omeprazole which may exhibit improved pharmacokinetic and metabolic properties and/or which may result in an improved therapeutic profile. Herein, we report our synthetic study of esomeprazole sodium Polymorphic form.
Authors and Affiliations
A. V. G. S. Prasad
Keywords
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