SYNTHESIS AND SPECTRAL CHARACTERIZATION OF SOME TRANSITION METAL COMPLEXES OF AZO-SCHIFF BASE DERIVATIVE OF METOCLOPRAMIDE
Journal Title: World Journal of Pharmaceutical Research - Year 2018, Vol 7, Issue 6
Abstract
A new Azo-Schiff base ligand L was prepared by reaction of azoaldehyde with Metoclopramide (2-(diethylamino)ethyl 4- aminobenzoate). This synthesized ligand was used for complexation with different metal ions like Ni (II), Co (II), Cu (II) and Cr (I11) by using a molar ratio of ligand: metal as 2: 1. Resulted compounds were characterized by NMR (1 H), UV–vis spectroscopy, FT-IR, MS, elemental analysis, and molar conductivity studies. The synthesized ligand and metal complexes were screened for antibacterial activity against some Gram-positive and Gram-negative bacteria.
Authors and Affiliations
Dr. Tarek A. Fahad
Keywords
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