SYNTHESIS AND SPECTRAL CHARACTERIZATION OF SOME TRISUBSTITUTED CYCLOHEXENONES
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2017, Vol 6, Issue 9
Abstract
A series of azachalcones had been prepared (1-14) via Claisen –Schmidt Condensation of 2-acetyl pyridine with different substituted benzaldehydes. The prepared azachalcones were brought to react with ethyl acetoacetate in the presence of sodium hydroxide to afford the title compounds (15-27). The structures of the final products were supported by spectral data (UV, IR, 1HNMR) in addition to their physical properties.
Authors and Affiliations
Abdul –Wahhab J. Al- Hamdany
A REVIEW ON PHARMACOVIGILANCE AND ITS IMPORTANCE
Pharmacovigilance defined by the world health organization as "the science and activities relating to the detection, assessment, understanding, assessment and prevention of adverse effects or any other drug related probl...
RESPONSE OF SOME MICROORGANISMS TO THERAPEUTIC (NEWLY EFFERVESCENT CIPROFLOXACIN AND CONVENTIONAL BRANDS)
Typhoid is an epidemic disease in Sudan and causes morbidity for many peoples especially in tropical countries.[1] This research aimed to study the response of (Salmonell typhi and Salmonella para typhi) to the ciproflox...
INDUSTRIAL PROCESS VALIDATION IN SOLID DOSAGE FORM: A REVIEW
The present article gives an introduction and general overview on process validation of pharmaceutical manufacturing process especially tablet manufacturing process. The concept of validation was first proposed by Food a...
PREPARATION AND EVALUATION OF GASTRORETENTIVE SYSTEMS OF TELMISARTAN
Telmisartan (TEL) is a selective angiotensin II receptor blocker used in the management of cardiovascular disorders. It is a class II drug according to biopharmaceutics classification system; with poor solubility and hig...
THE IMPACT OF HIV AND MALARIA CO-INFECTION ON CARDIAC BIOMARKERS AND CD4+ T CELL COUNTS IN ADULT HIV SEROPOSITIVES IN NAUTH NNEWI, SOUTH EASTERN, NIGERIA.
Aim: To determine the impact of HIV and malaria co-infections on Cardiac biomarkers and CD4+ T cell counts in adult HIV seropositives in NAUTH Nnewi, South Eastern, Nigeria. Methods: A total of 400 subjects aged between...