Synthesis, Characterization, and Antibacterial Activity of Some Novel 5-Chloroisatin Derivatives
Journal Title: International Journal of engineering Research and Applications - Year 2017, Vol 7, Issue 6
Abstract
The development of potential antibacterial requires the synthesis of a new series of 5- Chloroisatin derivatives incorporating various aromatic aldehydes in the case 1,3-Dipolar Cycloaddition including Nitrile oxide, as well as the cycloaddition Alcyne-Azide Catalytic with Copper. The charcterization of the structure of the synthesized compounds was confirmed by means of their IR, 1H-NMR and 13C-NMR spectral data. In addition, the antibacterial properties in vitro were tested against certain microorganisms using the disk diffusion technique. A majority of compounds show better activity against several of the microorganisms.
Authors and Affiliations
Z. Tribak, O. El Amin, M. K. Skalli, O. Senhaj, Y. Kandri. Rodi, M. Houssaini. Iraqui
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