Synthesis, Characterization, and Antibacterial Activity of Some Novel 5-Chloroisatin Derivatives
Journal Title: International Journal of engineering Research and Applications - Year 2017, Vol 7, Issue 6
Abstract
The development of potential antibacterial requires the synthesis of a new series of 5- Chloroisatin derivatives incorporating various aromatic aldehydes in the case 1,3-Dipolar Cycloaddition including Nitrile oxide, as well as the cycloaddition Alcyne-Azide Catalytic with Copper. The charcterization of the structure of the synthesized compounds was confirmed by means of their IR, 1H-NMR and 13C-NMR spectral data. In addition, the antibacterial properties in vitro were tested against certain microorganisms using the disk diffusion technique. A majority of compounds show better activity against several of the microorganisms.
Authors and Affiliations
Z. Tribak, O. El Amin, M. K. Skalli, O. Senhaj, Y. Kandri. Rodi, M. Houssaini. Iraqui
Keywords
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- EP ID EP391462
- DOI 10.9790/9622-0706046670.
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