Synthesis, Characterization and Biological activity of 3- Indole Acetic acid
Journal Title: International Journal of Novel Trends in Pharmaceutical Sciences - Year 2015, Vol 5, Issue 1
Abstract
On literature review, the studies on carboxylic acids reveal that their coordination chemistry has been studied extensively. However, in view of the absence of reports on the coordination chemistry of substituted acetic acid moieties the present investigation has been undertaken. In the present work, indole acetic acid (IAA) a base moiety was characterized by elemental analysis, Ultra Violet–Visible, FT-IR and 1H-NMR spectroscopy studies and the interaction of the base IAA with bivalent metal ions like cobalt (II), copper (II) and nickel (II) in non- aqueous media like ethanol was studied. The metal complexes of cobalt (II), copper (II) and nickel (II) ions with IAA are synthezised in solid state and their characterization was done by chemical analysis, electrical conductivity, elemental analysis and spectral measurement (UV-visible, FT-IR, and 1HNMR).Magnetic susceptibility values have also been measured for the complexes synthezised. The metal complexes have also been tested in vitro for their antibacterial and anti-fungal activity.
Authors and Affiliations
K Trinagaraju , A. V. G. S. Prasad , P. Venkateswara Rao , P. S. S. Prasad
Keywords
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