SYNTHESIS, CHARACTERIZATION AND EVALUATION OF ANTIBACTERIAL ACTIVITY OF COPPER(II) CHELATES OF 3-NITRO-1,5-DIARYLFORMAZANS
Journal Title: International Journal of Current Research and Review - Year 2017, Vol 9, Issue 4
Abstract
Copper(II) chelates of 3-nitro-1,5-diarylformazans have been synthesized by reacting aqueous solution of copper(II) acetate tetrahydrate with methanolic solution of the ligand. The so synthesized copper(II) chelates of 3-nitro-1,5-diarylformazans were purified, crystallized and characterized on the basis of elemental analysis, IR, Electronic and EPR spectral studies, and magnetic susceptibility measurements. The studies reveal that these copper(II) chelates of 3-nitro-1,5-diarylformazans characterized as bis-chelates having 1:2 stoichiometry, are paramagnetic in character and most probably have a symmetrical six membered chelate ring structure. The anti-bacterial activity of these bis(3-nitro-1,5-diarylformazanato)copper(II) chelates has been evaluated against Escherichia coli and Bacillus subtilisby disc diffusion method and compared with standard Amoxycillin and they are found to possess potent anti-bacterial activity against selected bacterial strains.
Authors and Affiliations
Manavjot Kaur
Keywords
Related Articles
- EP ID EP601091
- DOI -
- Views 99
- Downloads 0
Prevalence and Gender Differentials of Metabolic Syndrome Among College Students of Kolkata, West Bengal, India
Aim: The study aims to determine the prevalence of metabolic syndrome (MS) and assess gender differences among college students of Kolkata, West Bengal, India using International Diabetes Federation (IDF) criteria. Mater...
Ridge Augmentation Meet for Esthetics: An Interdisciplinary Approach
Aim: Dentoalveolar defects occur due to maxillofacial trauma, accidents, traumatic tooth extraction, advanced periodontal diseases, which results in loss of alveolar ridge and attached mucosa. These defects when occur in...
Profile of Metal Accumulation in Aquatic Macrophytes
Industrial development coupled with population growth has resulted in the over exploitation of natural resources. Life support systems viz; water, air and soil are thus getting exposed to an array of pollutants especiall...
ASSESSMENT OF KNOWLEDGE AND AWARENESS ABOUT PERIODONTAL ORAL HEALTH AMONG PREGNANT WOMEN- A QUESTIONNAIRE STUDY
Background: Periodontal diseases and systemic diseases are having association and various studies have been done to assess the scientific evidence. There are a lot of scientific data available to explain the association...
A Case of Neurofibromatosis Type 1 Associated with Cervical Cord Ependymoma
Patients with neurofibromatosis 1 (NF1) are predisposed to develop central nervous system tumours, due to the loss of neurofibromin, an inactivator of proto-oncogene RAS. We present a case of NF1 patient with a spinal co...