Synthesis, characterization and pharmaceutical applications of Curcumin metal complex
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 6
Abstract
Nowadays People are often down with dengue, pneumonia, and viral infected fever because of unclean surrounding. This is the first attempt to use curcumin complex in a model anti-bacterial assay experiment on Staphylococcus aureus, E. coli, Klebsiella pneumonia and Pseudomonas fluorescence.Results show thatcurcumincomplex has significant higher activity compared to pure curcumin. Curcumin copper complex was synthesized by using DMSO and ethanol solvent mixture at 350oC and characterised by FT- IR spectral analysis. The compound was used to assay the anti-bacterial activity on Staphylococcus aureus, E. coli, Klebsiella pneumonia and Pseudomonas fluorescence. Minimuminhibition zone for the four pathogens bacterial were compared. On the basis of MCI zone area the activity of the complex is as follows Klebsiella pneumonia>,E.coli,> Staphylococcus aureus> Pseudomonas fluorescence. Our results provide a promising role to use copper- curcumin complexes in diverse biological applications.
Authors and Affiliations
Dr. A. Gubendran*, Dr. M . Amutha3,, P. Dhanasekaran, A. Imayatharasi, M. Vijayalakshmi 2
Keywords
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- EP ID EP386788
- DOI 10.9790/3008-1106038084
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