Synthesis, Charecterization And Antibacterial Activity of Some Novel Chalcones And Its Derivatives
Journal Title: IOSR Journal of Applied Chemistry (IOSR-JAC) - Year 2018, Vol 11, Issue 8
Abstract
Chalcones, (E)-N-(4-(4,6-dichloro-1,3,5 –triazin-2-ylamino) phenyl)-3-(4-methoxyphenyl) acrylamide (4a-c) have been prepared according to Claisen-Schmidt condensation. Further these chalcones (4a-c) on reaction with malononitrile affords cyanopyridines (5a-c) and on reaction with hydrazine hydrate affords pyrazole (6a-c) respectively. The constitutions of newly synthesised compounds have been characterized on the basis of their IR and 1H NMR, 13C NMR spectral data.These synthesized compounds have been screened for their antibacterial activity.
Authors and Affiliations
M. Thamizhthendral, S. Syed Shafi
Keywords
Related Articles
- EP ID EP414378
- DOI 10.9790/5736-1108012732.
- Views 199
- Downloads 0
Iron and Malachite Green Removal By Adsorption Mangifera Indica (Mango Tree Leaf) Shell As Low Cost Adsorbent
Eco-friendly adsorbent has been reported as an alternative to the current expensive methods of removing of iron and malachite green (MG) dye from aqueous solution. Iron is also an essential constituent of human body whic...
Effect of Pyridine on the Corrosion Behavior of Electrodeposited Ni-Co Alloy Thin Films and Their Structural and Morphological Analysis
Ni-Co thin films have been grown on Stainless steel substrate by galvanostatic electrodeposition from Sulphate baths containing Pyridine as Organic inhibitor. A comparative study of corrosion parameters were done in thre...
Statistical Trends in Literacy Rates in Nepal
The history of education system is not so long in Nepal. The common Nepalese people did not get the formal education at the time of Rana regime. At that time, education system of Nepal was in a very deprived condition. A...
Impact of Urbanization on the Physicochemical Parameters of an Urban Water Body of Bellandur Lake in Bangalore City, Karnataka, India
Lake Water is a source of drinking and domestic use for rural and urban population of India. The once bountiful Bellandur Lake has gradually transformed into a sewage tank. Bellandur Lake is one of the largest lakes in t...
Quantative Determination of Aromatic Phenols with NBSA Reagent
An accurate method has been described for determination of Aromatic phenols & its derivatives at micro scale using N-bromosaccharin as brominating & oxidizing agent. A known volume of sample solution of Aromatic phenols...