Synthesis of Fluorinated Pyridines as 19F NMR pH Indicators
Journal Title: JOURNAL OF ADVANCES IN CHEMISTRY - Year 2014, Vol 10, Issue 3
Abstract
This research was undertaken to synthesizes and evaluate 3,5-dihydroxymethyl-4-(2-fluorophenyl)-2,6-dimethylpyridine and 4-(fluoromethyl)-2,6-dimethylpyridine as indicators of 19F NMR pH. A comparison of 3,5-dihydroxymethyl-4-(2-fluorophenyl)-2,6-dimethylpyridine to 4-(fluoromethyl)-2,6-dimethylpyridine showed that 4-(fluoromethyl)-2,6-dimethylpyridine has a large 19F chemical shift to pH, a suitable pKa value and a good water solubility.
Authors and Affiliations
Mohammad Ali Amrollahi
Performance of Al-si-glass fiber composite piston in an IC Engine
The piston is one of the major part of the automobile. The piston purpose is to transfer force from expanding gas in the cylinder to the crankshaft. The piston acts as the vital link between the generation of power insid...
THE INHIBITION AND ADSORPTION PROPERTIES OF DTPMP TSC ON STAINLESS STEEL IN ACIDIC MEDIUM
The inhibition effect of diethylenetriamine penta(methylene phosphonic acid) (DTPMP) and Trisodium Citrate (TSC) on thecorrosion behavior of stainless steel in 0.5 M H2SO4 solution was investigated by using weight loss m...
Removal of BTEX from aqueous solutions by paper mill sludge-based activated carbon
The removal of BTEX (benzene, toluene, ethyl-benzene and p-xylene) from contaminated groundwater was evaluated by paper mill sludge-based activated carbon, prepared by chemical activation and pyrolysis.The effects of pH,...
Synthesis and Antitubercular Evaluation of Some Novel 1,2,3,6-tetrahydropyrimidine-5-carbonitrile
     In an attempt to find a new class of antitubercular agents, a series of 1,2,3,6-tetrahydropyrimidine-5-carbonitrile were prepared via the reaction of ethyl N-ethoxycarbonylbenzimidate 2a-b with cyanoaceta...
Myths and verities in protein folding theories Part I: Anfinsen hypothesis and the search for the global minimum in the Gibbs energy landscape
Anfinsen’s thermodynamic hypothesis may be interpreted in two ways: One, that the native 3D structure of the protein, resides in the absolute minimum in the Gibbs energy landscape (GEL). The second, that the Gibbs ener...