Synthesis of Hydrogels Containing Halloysite and Investigation of Antiproliferative Activity
Journal Title: Advances in Clinical Toxicology - Year 2023, Vol 8, Issue 3
Abstract
In this study, superabsorbent hydrogels containing halloysite clay, biopolymer (CMC, carboxymethyl cellulose), acrylamide (AM) and 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS) were synthesized and characterized by free radical polymerization method. Then, the cytotoxic effect of hydrogels on MDA-MB-231 breast cancer cells was evaluated. According to the findings, hydrogels were successfully synthesized and their cytotoxic properties were supported by in vitro studies. In order for these hydrogels to be used as a drug delivery system, their potential properties need to be supported by further research such as in vivo.
Authors and Affiliations
Sökmen O, Çankaya N* and Azarkan Yalcin S
Keywords
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