Synthesis of Hydrogels Containing Halloysite and Investigation of Antiproliferative Activity
Journal Title: Advances in Clinical Toxicology - Year 2023, Vol 8, Issue 3
Abstract
In this study, superabsorbent hydrogels containing halloysite clay, biopolymer (CMC, carboxymethyl cellulose), acrylamide (AM) and 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS) were synthesized and characterized by free radical polymerization method. Then, the cytotoxic effect of hydrogels on MDA-MB-231 breast cancer cells was evaluated. According to the findings, hydrogels were successfully synthesized and their cytotoxic properties were supported by in vitro studies. In order for these hydrogels to be used as a drug delivery system, their potential properties need to be supported by further research such as in vivo.
Authors and Affiliations
Sökmen O, Çankaya N* and Azarkan Yalcin S
Keywords
Related Articles
- EP ID EP752287
- DOI 10.23880/act-16000274
- Views 7
- Downloads 0
Herb Induced Aconite Poisoning and Bidirectional Ventricular Tachycardia
Aconite is a potent cardiotoxic compound and the cardio toxicity gets manifested by hypotension, ventricular tachycardia, and even cardiac death. Herbal medicines may contain aconite as an active gradient, and ingestion...
Genotoxicity, Acute and Sub-Chronic Toxicity Studies of Solid-State Cultivated Mycelial Powder of Antrodia cinnamomea
Antrodia cinnamomea is a precious medicinal mushroom endemic to Taiwan that has been used as folk medicine for health promotion and treating various diseases. In this study, the toxicological assessment of solid-state c...
Glucose Transporter 4, Biomarker Development and Metabolic Syndrome in the Arctic
A general hindrance to research and clinical surveillance in the Arctic and sub-Arctic is the lack of early measured, supporting biomarkers for risk assessment. The increasing prevalence of visceral obesity is a risk fa...
Adolescent Obesity and Psychiatric Co-Morbidities: A Dire Need for Lifestyle Modifications and Interventions
Due to the severity of metabolic dysfunction, obesity raises the incidence of anxiety and depression. Adolescents with depression had a 40% higher risk of being obese, whereas obese adolescents had a 70% higher risk. Ove...
Some Aspects of Interactions between Nanomaterials and the Cytoskeleton of Eukaryotic cells
All cellular functions are primarily related to the behavior of the components of cell and its cytoskeleton. Cells in the various tissues respond to the sudden changes in their ambient environment may it be biochemical,...