Synthesis of some new Schiff bases of Pharmaceutical Interest
Journal Title: Annals of Advances in Chemistry - Year 2017, Vol 1, Issue 1
Abstract
A series of Schiff bases of diphenylamine derivatives have been synthesized and evaluated in vitro for their antibacterial activity against pathogenic both Gram-positive bacteria B. subtilis and Gram-negative bacteria E. coli using ciprofloxacin as standard drug at conc. of 50 µg/ml and 100 µg/ml. The structures of these compounds were established on the basis of IR and 1H-NMR spectral analysis. The compound (3d) displayed potent antibacterial activity against Bacillus subtilis (17 and 15mm) and Escherichia coli (19 and 17mm) by disc diffusion method.
Authors and Affiliations
A Kumar, S Verma, AK Mishra
Keywords
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- EP ID EP541813
- DOI 10.29328/journal.aac.1001006
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