SYNTHESIS OF TRANSITION METAL ION COMPLEX OF 2- AMINOBENZOXAZOLE AND ANTIFUNGAL ACTIVITY AND ROLE IN PHARMACEUTICAL CHEMISTRY

Abstract

In view of the fact that a large number of derivatives of benzoxazole have been found to exhibit a wide variety of antimicrobial activities. Heterocyclic compounds play an important role in medicinal chemistry and exhibit wide range of biological activities in pharmaceutical chemistry. Complexes of 2-aminobenzoxazole (L) with chloride of iron (II), was synthesized. The molar ratio metal: ligand in the reaction of the complex formation was 1:2. It should be noticed, that the reaction of all the metal salts yielded bis (ligand) complex of the general formula M (L) 2(CL) 2. The complex was characterized by elemental analysis, melting point, FT-IR, 1H NMR, spectral data. The antifungal activity against different fungai, A.niger, A.flavus, Fusarium oxysporum, paecilomyces variotii, C.albicans.

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  • EP ID EP261509
  • DOI 10.5281/zenodo.1163005
  • Views 114
  • Downloads 0

How To Cite

(2017). SYNTHESIS OF TRANSITION METAL ION COMPLEX OF 2- AMINOBENZOXAZOLE AND ANTIFUNGAL ACTIVITY AND ROLE IN PHARMACEUTICAL CHEMISTRY. INTERNATIONAL JOURNAL OF ENGINEERING TECHNOLOGIES AND MANAGEMENT RESEARCH, 4(12), 60-64. https://europub.co.uk/articles/-A-261509