Synthesis, study and antimicrobial activity of new homo, copolymer maleic anhydridse with moiety heterocyclic creatinine
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 4
Abstract
The presented work involved the preparation of polymers homo and copoly containing heterocyclic (creatinine) derived from Maleic anhydride. The first step involved the preparation of maliamic acidcreatinine derivative,by reaction of maleic anhydride withcreatinine.The second step includes the polymerization of the prepared homo andcopolypolymersby free radical polymerization using (BPO) as initiator with heating. The third step involves study of degredation analysis of polymer in different at 370C using UV-Visible spectroscopy ,thermal analysis andSwelling studies . polymers were characterized by softening points , with other physical properties, FTIR, H1-NMR spectra, and thermal analysis (DSC),screening of the antimicrobial activity of the prepared polymers was evaluated against 3 types of bacteria.
Authors and Affiliations
Muna. I . Khalaf*, Mayson. K. Hussein
Keywords
Related Articles
- EP ID EP390387
- DOI 10.9790/3008-1204082935
- Views 67
- Downloads 0
Studies on Skin Sensitivity to Various Allergens in Jeddah, Saudi Arabia Using Skin Prick Test
Skin prick test is one of the more important diagnostic tests against allergic diseases, it uses a synthesized allergic extracts from different allergens. In this study skin prick test was done on 83 allergic persons and...
Germplasm Preservation And Propagation; The Foundation Of Agricultural Development –A Review
The whole set of genetic material of a species of plants is known as germplasm of the organisms. Through various breeding techniques the germplasm of various plant species can be stored or preserved for future plant deve...
Tailor Made Phospholipid Based Curcumin Phytosomes: Fabrication, Characterization and Ex-Vivo Permeation
Curcumin (CUR), a highly lipophilic molecule has wide range of pharmacological activities. Nevertheless its limited aqueous solubility and extensive pre-systemic metabolism confine its bioavailability. CUR phytosomes wer...
Evaluation of Plasma Creatine Kinase Activity and Inorganic Phosphate among Sudanese Patients with Sickle Cell Disease in Khartoum and White Nile State
Background: CK and phosphorus are helpful biomarker for detection of early renal abnormality particularly CK which has been shown to be abetter predicator of acute renal failure. Objectives: This is a descriptive cross-s...
Effect of Excipients on the Release of Simvastatin from Biodegradable Polymeric Implant
The objective of the present study was to develop and evaluate a sustained release Gelatin-sodium alginate biodegradable polymeric implant containing Simvastatin, an inhibitor of 3-hydroxy-3-methylglutarylcoenzyme A (HMG...