Synthesis, study and antimicrobial activity of new homo, copolymer maleic anhydridse with moiety heterocyclic creatinine
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 4
Abstract
The presented work involved the preparation of polymers homo and copoly containing heterocyclic (creatinine) derived from Maleic anhydride. The first step involved the preparation of maliamic acidcreatinine derivative,by reaction of maleic anhydride withcreatinine.The second step includes the polymerization of the prepared homo andcopolypolymersby free radical polymerization using (BPO) as initiator with heating. The third step involves study of degredation analysis of polymer in different at 370C using UV-Visible spectroscopy ,thermal analysis andSwelling studies . polymers were characterized by softening points , with other physical properties, FTIR, H1-NMR spectra, and thermal analysis (DSC),screening of the antimicrobial activity of the prepared polymers was evaluated against 3 types of bacteria.
Authors and Affiliations
Muna. I . Khalaf*, Mayson. K. Hussein
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