Systematic analysis of components and contents in Houttuynia cordata Thunb
Journal Title: Traditional Medicine Research - Year 2017, Vol 2, Issue 4
Abstract
Objective: This study aims to provide the material basis for the molecular mechanism of Yuxingcao (Houttuynia cordata Thunb, HCT) through the method of evidence-based study to summarize the natural constituents isolated from HCT. Methods: We searched CNKI, Wanfang, VIP, Pubmed and relevant conference compilations. The keywords were “Yuxingcao or Houttuynia cordata Thunb” and “components” or “ingredients” or “constituent” or “volatile oil” or “flavonoids” or “terpene” or “content”, both in Chinese and English. According to the inclusion and exclusion criteria, the reported compositions and contents have been summarized, and SPSS software was used to draw the boxplot of contents. Results: A total of 603 natural compounds in 11 categories were obtained from pooled articles. In the diverse components, the number of aliphatic compounds (n = 259) and terpenoids (n = 158) are more than those of flavonoids (n = 26), alkaloids (n = 42) and aromatics (n = 42). While, in the part of volatile oils of HCT, the largest components are aliphatic compounds (mainly distributed on the ground) and terpenoids (mainly distributed in the underground). Although, methyl n-nonylketone is distributed in the whole herb plant, a large proportion is present in the underground parts. As for non-volatiles, the flavonoid content (mainly distributed on the ground) was the highest, among which quercetin and its glycosyl derivatives were the prominent. Conclusion: The results of this study provide a more comprehensive material basis for the further study of HCT. It is also helpful to explain the mechanisms of anti-oxidant, anti-inflammatory, anti-bacterial, anti-viral and anti-cancer effects from the molecular target and molecular network levels.
Authors and Affiliations
Dong Xin-Yi, Jin Yi, Yang Li-Ping
Investigation of the processing technology and mechanism of Kansui radix by licorice based on response surface methodology and integrative pharmacology
Background: The herbs should be processed by different methods before use, and the efficacy and toxicity of Chinese herbal medicines may change, which may enhance efficacy and reduce toxicity after processing. Gansui (Ka...
Does Liuzijue Qigong affect anxiety in patients with chronic obstructive pulmonary disease, even during the COVID-19 outbreak? a randomized, controlled trial
Background: Anxiety is a common comorbidity associated with chronic obstructive pulmonary disease (COPD), but no well-recognized method can provide effective relief. Liuzijue Qigong (LQG) is a traditional Chinese fitness...
Complete response of hepatocellular carcinoma treated with traditional Chinese medicine treatment: A case report
We reported a detailed clinical course of complete response of hepatocellular carcinoma(HCC) with traditional Chinese medicine(TCM) treatment in the present study. In June 2011, a 47-year-old man was admitted to our hosp...
The riddles of number nine in Chinese medicine processing method
The “nine cycles of steaming and shining”, “nine making”, “nine turns” and “nine cycles of calcining and quenching” methods that are recorded and used since ancient times are merely one aspect of the unique processing me...
Effects of Danchai formula on regulation of immunologic function
The traditional formula of Danchai was provided by associate professor Dan Chen of Tianjin Medical University, which consisted of Chaihu (Radix Bupleuri) 9 g, Baishao (Radix Paeoniae Alba) 9 g, Yujin (Radix Curcumae) 30...