Systemic Sclerosis: A Multiorgan Disease, Types and Symptoms
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2017, Vol 1, Issue 1
Abstract
Systemic Sclerosis is a chronic condition caused by excessive secretion of collagen inside the body. Some consider it a chronic condition of the connective tissue in the body. Although it is not contagious or cancerous, it may threaten life depending on the severity of the disease. Syatemic sclerosis affects the body’s organs as one of the rheumatic autoimmune diseases, which means that the body’s immune system behaves abnormally. The main result of this is the so-called hardening of the skin and the appearance of infections and ulcers in many parts of the body, Lungs, kidneys, heart, intestinal tract and other organs, and yet there is no cure for hardened skin but alternative treatments are effective for some forms of disease available. This mini review aims to disclose some important aspects of this multiorgan disease. Systemic sclerosis is considered one of the rare immune diseases that afflict the connective tissue. Skin stiffness is the most important characteristic of this disease, although hardening of the skin may occur in another type of disease known as the sclerosis, which is different from the general sclerosis in that it does not affect the organs Interior [1]. The disease is characterized by vasoconstriction, with the proliferation of cells lining the wall and increased vascularity of constriction, which may expose the organs infected with vascular insufficiency of severe circulation in the blood, in addition to the presence of inflammation of infected organs and cirrhosis of the skin and internal organs. The disease affects the females three to five times its effect on males, especially in the age of fifteen to forty years of age. The disease usually affects people between 30 and 50 years of age and rarely develops in children. Is not fully aware of the actual cause of the disease and genetic factors are involved in a limited extent in the cause of the disease. Infection with the cytomegalovirus may affect the immune system of the disease. A close relationship has been found between exposure to organic solvents, chemicals and general sclerosis [1,2].
Authors and Affiliations
Chateen I Ali Pambuk, Fatma Mustafa Muhammad
Keywords
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- EP ID EP567445
- DOI 10.26717/BJSTR.2017.01.000143
- Views 147
- Downloads 0
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