Systemic sclerosis and tuberculosis – A case report
Journal Title: International Archives of Integrated Medicine - Year 2017, Vol 4, Issue 10
Abstract
Scleroderma is a chronic systemic autoimmune disease of unknown origin characterized by excessive collagen deposition and autoantibodies. Patients with autoimmune diseases are known to develop infections like tuberculosis due to the disease per se and also secondary to immunosuppressive treatment. Mycobacterial infections are also known to induce the development of autoantibodies. We present a case of simultaneous occurrence of interstitial lung disease and pulmonary tuberculosis (BAL positive for AFB) in a patient with features of systemic sclerosis. Antibody profile was done were found to be positive for ANA. She also had most of the classical features of scleroderma on clinical examination thus confirming the diagnosis. A detailed history, clinical examination, radiological examination, bronchoscopy and immunological test helped in the diagnosis of the patient. We highlight the importance of suspicion, careful general examination, radiological assessment and screening tuberculosis patients for autoantibody profile in presence of a multisystem involvement.
Authors and Affiliations
S. Uma Ganesh, Krishnapriya R. , R. Srinivasan
Keywords
Related Articles
- EP ID EP411553
- DOI -
- Views 139
- Downloads 0
Clinical profile of abdominal tuberculosis presenting to a tertiary care teaching hospital - A prospective observational study
Introduction: Tuberculosis was the major infectious cause of death in the world. Even though, in developing western countries it is less common the mortality rate of abdominal TB was because of less awareness, and lack o...
A study of expression of BCL-2 in colorectal carcinoma with histopathological correlation
Introduction: Colorectal cancer is the major cause of mortality and morbidity worldwide. Incidence in males - 4.3 /1, 00,000, in females - 3.4/1,00,000. The etiology of colorectal cancer is complex, involving interplay o...
A study of morbidity and mortality profile of 500 road traffic accident cases in Malwa region of Punjab
Background: Road Traffic Accidents (RTA) are increasing in an alarming ways. Globally, nearly 1.2 million people killed in RTA during the year 2002. Developing and underdeveloped countries accounted for 80% of these deat...
A prospective study of immediate maternal and neonatal effects of forceps and vacuum assisted deliveries
Introduction: The unaided human birth process is not perfect. All round the world 10% to20% of all pregnant women receive assistance with their delivery. Aim: This present study was to analyze and study the contribution...
Role of Fiberoptic Bronchoscopy in Histopathological Analysis of Lung Lesions
Introduction: Bronchogenic lesions are undoubtedly one of the most common diseases worldwide. Pulmonary cytology and biopsy are simple and resourceful methods of early diagnosis of respiratory diseases. The use of bronch...