Systemic sclerosis, secondary Sjogrens syndrome with corneal oedema: A case report
Journal Title: Journal of Medical and Scientific Research - Year 2016, Vol 4, Issue 4
Abstract
Purpose: To present a case of systemic sclerosis with asymmetrical skin involvement, decreased tear production not responding to topical cyclosporine therapy and corneal edema in one eye. Methods: An 84 years old female diagnosed with scleroderma two years ago presented with history of decreased vision in the left eye of 10 days duration. Results: She had generalised tight skin which was more on the left side. The skin of the face including the eyelids was tight. Her best corrected visual acuity was 20/30, N6 in the right eye and in the left eye, it was 20/200. The Schirmer’s test without anaesthesia revealed a value of 3 mm in the right eye and 1 mm in the left eye. Anterior segment evaluation showed clear cornea with no guttata in the right eye. In the left eye, there was stromal oedema involving inferior half of the cornea with superficial blood vessels inferiorly. Both the corneas showed central superficial punctuate keratopathy. Anterior segment optical coherence tomography showed normal cornea in the right eye, whereas in the left eye there was hyper-reflectivity at the level of Descemet’s membrane suggestive of increased fibrosis and the corneal thickness was more. Conclusions: Systemic sclerosis can present with asymmetrical skin involvement, decreased tear production not responding to topical cyclosporine therapy and corneal edema in one eye. Further studies are warranted to develop treatment strategies of managing corneal edema in systemic sclerosis.
Authors and Affiliations
Sridhar MS
Study of seasonal variations in the incidence of postoperative laryngospasm
Laryngospasm causes about 40% of post-extubation airway obstruction. The incidence of laryngospasm in paediatric population ranges from 0.04 to 14%. Despite advances in monitoring and in the standard of care in the pract...
Supra ventricular tachycardia (SVT)
Abstract is not available for this article
Recent significant advances in medicine
Experimental cancer therapeutics delivered to tumors via nanoparticles could provide a safer and more effective therapy compared to conventional chemotherapy.
Left diaphragmmatic eventration with gastric volvulus: Laparoscopic mesh repair of left diaphragmatic eventration
Background: Eventration of diaphragm is defined as an abnormal elevation of an intact diaphragm and most often is characterized by a developmental abnormality of the diaphragm musculature. It usually remains asymptomatic...
A comparative study of anxiety and depression among adolescents from rural and urban areas
Introduction: Depression and anxiety are commonly reported issues among adolescents populations. These will affect student’s interpersonal skills and can impede their ability in their performance due to drop in the neuro...