Syzygium sp (Myrtaceae) Extracts: Inhibition of Alpha Amylase
Journal Title: European Journal of Medicinal Plants - Year 2014, Vol 4, Issue 1
Abstract
Aims: The aims of this study were: a) prepare crude extracts of commercial teas Syzygium sp by different methods (maceration, decoction and infusion) in different proportions (1:20, 1:50 and 1:100) and b) submit them the inhibition assays digestive enzyme alpha-amylase before and after exposure to a simulated gastric fluid. Place and Duration of Study: Laboratório de Bioquímica, Instituto de Ciências Biológicas e Naturais, Universidade Federal do Triângulo Mineiro, Brazil, between August 2012 and July 2013. Methodology: Five samples of Syzygium sp teas were purchased commercially from pharmacies, drugstores and health food stores. Results: In the first step - inhibition of enzymatic extracts of the teas without simulated gastric fluid - the results showed significant inhibition of alpha-amylase (mean 92.84%, CV = 3.86%). However, when these extracts were placed in contact with the simulated gastric fluid was observed decreased inhibition of alpha – amylase, suggesting a possible reduction of hypoglycemic potential of these teas under physiological conditions. Conclusion: Aqueous extract Syzygium sp have high percentages of inhibition of the enzyme amylase, suggesting a potential hypoglycemic effect. Additional studies aiming at elucidating the chemical compounds present in the extracts of Syzygium sp using chromatographic techniques will be performed.
Authors and Affiliations
Tuanny Cavatão de Freitas, Chrystian Araújo Pereira, Luciana Lopes Silva Pereira
Keywords
Related Articles
- EP ID EP350027
- DOI 10.9734/EJMP/2014/6781
- Views 71
- Downloads 0
Berberis vulgaris/Picrorhiza kurroa: Extending the Treatment Window for Reperfusion Injury
Aims: The present study investigates the neuroprotective effects of Berberis vulgaris and Picrorhiza kurroa in a rodent model of cerebral ischemia – reperfusion. Study Design: Rats were pretreated with Berberis vulga...
Evaluation of Multiple Functions of Polygonum Genus Compounds
For thousands of years, traditional medicinal plants have been used to control several diseases, based on traditional knowledge and experience. Nevertheless, many potential medicinal plants have not attracted attention t...
Inhibition of Microsomal Lipid Peroxidation and Protein Oxidation by Carica papaya (L) Leaf against Carbon Tetrachloride-Induced Hepatic Injury in Wistar Albino Rats
Aims: To investigate the hepatoprotective activities of C. papaya leaf in Carbon tetrachloride induced hepatic damage in albino rats. Place and Duration of Study: Department of Medical Biochemistry, Faculty of Basic Med...
Antioxidant Activity and Phytochemistry Study of Combretum obanense Stem (Bak. F) Hutch. and Dalz
Objective: The objective of the present study was designed to test the antioxidant activity and phytochemical property of the methanol/ methylene chloride (1:1) extract of Combretum obanense. Place and Duration of Study:...
Antiplasmodial Potential of Traditional Medicinal Plant Thlaspi arvense
Aim: Antiplasmodial potential of traditional medicinal plant Thlaspi arvense against Plasmodium falciparum in vitro has been evaluated. Cytotoxicity of plant extract against HeLa cell lines and normal fibroblasts has als...