Tal Sindoor: an in vivo study
Journal Title: Journal of Ayurvedic and Herbal Medicine - Year 2016, Vol 2, Issue 2
Abstract
Tal Sindoor is one of Ayurvedic metallic preparations processed by Kupipakwa method (special processing). As per the present day scenario intake of formulations prepared with heavy metals like mercury and mineral compound like arsenic trisulphide are considered highly toxic. Tal Sindoor is prepared with Shuddh (purified) Parad (mercury), Gandhak (sulphur) and Haratal (arsenic trisulphide). With the myth that Rasoushadhis (metallic preparations) are toxic, the need for the study was persuade to elucidate the safety of diligently processed Tal Sindur at therapeutic dose prescribed in classics. Study was conducted for 14days on Wistar strain albino rats. Selected Wistar strain albino rats were divided into two groups. Group-I being vehicle control group, albino rats were administered with 0.5ml of compound consisting of 3 parts of de-ionized water and 2 parts of honey. Group-II rats were administered with 0.5ml of compound vortexes with test compound Tal Sindoor at therapeutic dose of 250mg/Kg/day in 3 parts of de-ionized water and 2 parts of honey. During or after the study either morbidity or mortality was not observed. Food and water intake, body weight, normal activity, behavioural changes and other toxicological changes were evaluated daily for both groups during administration of drugs. After the study haemotological, biochemical parameters, lipid-peroxidation and histopathological changes were evaluated for both the groups. Statistics of body weight and above mentioned parameters were not significant. Histopathological examination of liver and kidney revealed normal histology for both groups.
Authors and Affiliations
Dasari Srilakshmi, T. Anand, Farhath Khanum
Pharmaceutical and analytical profiles of Savarnakara Yoga
Background: Savarnakara Yoga is a herbo-mineral formulation mentioned in different Ayurvedic classics for management of shvitra. It contains Bakuchi (Psoralia corilifolia Linn.) and Haratala (Orpiment), which are well-kn...
A Case Study On The Management of Beejadushtijanya Pandu (Thalassemia Major) in Children with Gandhakadi Yoga
Introduction: The classical formulations are amended from time to time according to the need of healthy as well as disease conditions. This flexibility has insured its existence until today. Thalassemia is a genetic bloo...
Overview of Pentatropis capensis (Asclepiadaceae)- An Extra Pharmacopoeial Plant
Plants are a rich source of many natural products. In India, most of which have been extensively used for traditional human health care systems viz. Ayurveda, Unani and Siddha. Most of these pharmacopoeial unidentified d...
Sensitivity of Candida albicansto aqueous and alcohol extracts of four medicinal plants
Candida albicansadimorphic fungus that exists as a commensal of warm-blooded animals including humans. Candida albicans infection raises a number of challenges including resistance of Candida albicans to the commonly use...
Effect of Yoga on Endocrine and Nervous System in Adolescent children: Assessment Using EPI parameters
Behavioral problems are highly prevalent in adolescent children. Adolescence is characterized by several major morphological and functional / behavioral changes. Hyper activities at endocrine and nervous systems seem to...