Temporal Bone Squamous Cell Carcinoma the Outcome of Radical Surgery as an Initial Treatment
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2014, Vol 4, Issue 12
Abstract
Aims: The aim of this study is to analyse the clinical data and management of patients with temporal bone carcinoma and to discuss the management outcomes. Study Design: Retrospective study Place and Duration of Study: Universiti Kebangsaan Malaysia Medical Centre (academic tertiary centre) from January 2002 to December 2011. Methodology: Medical records of nine patients were retrieved for this study. There were seven male and two female patients. The mean age of presentation was 60 years old, with an age range between 49 to 75 years. The clinical presentations, investigations, staging, treatment modalities and outcomes are reviewed. Results: Four patients presented with primary tumour of the temporal bone, while the remaining five were referred from other centres with disease recurrence. Only one out of the five patients that were referred to us had underwent a lateral temporal bone resection (LTBR) at presentation which was however an incomplete LTBR. Three out of the five patients (60%) have died with disease recurrence. One patient remained disease free while another patient was lost to follow up. Two out of the four patients who presented with primary tumour remained well while two others had positive margins due to advanced disease at presentation. Conclusion: Recurrence of disease is likely to occur if aggressive treatment is not offered at presentation or if the diagnosis is delayed. We therefore strongly suggest for early referral to a tertiary centre as aggressive primary surgical treatment with adjuvant radiotherapy shows a better prognosis.
Authors and Affiliations
Noor Liza Ishak, Bee See Goh, Lokman Saim
Effectiveness of HIV Anti-retroviral Agents on the HIV/AIDS Epidemic
Aims: The scale up of HAART globally has shifted the mortality time table, decreased viral transmission and improved health related quality of life for patients while emphasizing the importance of adherence to therapy fo...
Health Promotion of Young University Students in Lebanon: Physical Activity Behavior and Cultural Barriers
The aim of the present study was to assess the prevalence of physical activity (PA) and exercise behaviors in young students and to propose an evidence-based exercise practice program for undergraduates in a university s...
Predictors of Factors Sustaining HIV/STI Protective Behaviours among Adolescent Girls and Young Women in Mukuru Slums, Nairobi: A Retrospective Cohort Study
Aims: To identify factors which contribute to sustained human immunodeficiency virus protective behaviours for out-of-school slum-dwelling young women aged 15-24 years by assessing consistent condom use and having one se...
Comparison of the Effect of Transpalatal Arch on Periodontal Stress and Displacement of Molars When Subjected to Orthodontic Forces. A Finite Element Analysis
Introduction: The transpalatal arch has been used successfully for decades during routine orthodontic treatment for various purposes, including reinforcing anchorage. In the light of current scientific advancements with...
An Overview of Hutchinson Gilford Progeria Syndrome (HGPS)
Hutchinson Gilford Progeria Syndrome (HGPS) is a rare genetic disorder. The disorder is characterized by premature aging, generally leading to death. The purpose of this article is to review Hutchinson Gilford Progeria S...