The Active Model: The E ect of Sti ness on the Maximum Amplitude Displacement of the Basilar Membrane
Journal Title: Journal of Advances in Mathematics and Computer Science - Year 2017, Vol 20, Issue 6
Abstract
The human cochlea is the part of the inner ear where acoustic signals are transformed into neural pulses and then signaled to the brain. The cochlear ampli er is essentially a positive feedback loop within the cochlea that ampli es the traveling wave, this mechanism based on the cochlea's microanatomy, as well as, outer hair cell force, to account for the cochlea's characteristic behavior. A proposed theory of the active cochlea that the feed-forward/feed-backward are two mechanisms for the outer hair cell force ampli cation where an expanding hair cell gives a forward push through the Deiters Cells and a backward pull on the Basilar membrane through the Phalangeal process. Many important questions of cochlea mechanics are mathematically complicated, however, they can be studied using numerical simulations. Genetic mutations of type IV collagen lead to a malfunction of Basilar Membrane, resulting in the hearing loss associated with Alport Syndrome, which is a disease that a ects the cochlea due to the abnormal structure of the Basilar Membrane (it becomes sti er). Therefore, a mathematical model of the BM was developed to investigate and show numerically the e ect of the sti ness on its structure with the objective to study the ear dysfunction in the active cochlea.
Authors and Affiliations
Fatima-Ezzahra Aboulkhouatem, Fatiha Kouilily, Mohammed EL Khasmi, Naceur Achtaich, Noura Yous
Keywords
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- EP ID EP322700
- DOI 10.9734/BJMCS/2017/30856
- Views 86
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