The Antibiotic and Garlic Susceptibility of Escherichia coli Strains and Their Ability of Attachment and Biofilm Formation
Journal Title: Scholars Academic Journal of Pharmacy - Year 2018, Vol 7, Issue 8
Abstract
Abstract: This study consisted on the impact of antimicrobial agents on Escherichia coli (E. coli) isolates and their power to adhere to surface for biofilms formation. Sixty two E. coli isolated from patients urines were then used for standard antibiograms on Mueller Hinton (MH) agar associated with garlic juice antimicrobial activity. The attachment of three E. coli strains selected according to their susceptibility to antibiotics was experimentally performed on glass slides and the adhesion profiles were determined to assess their power of biofilm formation. As results, even though, the dominant types of resistance were respectively to amoxicillin, tetracycline, ampicillin and nalidixic acid in more than 80% of all the E. coli isolates, the highest sensitivity were observed with Gentamycin in 81% and imipenem in 97% of all the samples. In addition, the tests of adhesion revealed that, significantly (p <0.0001), the three E. coli attachment to surface increased with their resistance to antibiotics. However, none of them resisted the garlic juice as well as isogenic planctonic-growing bacteria as biofilm-ones.
Authors and Affiliations
Kossi Bagoudou, Kodjovi Agbodeka, Banfitebiyi Gambogou, Komivi Gbada, Essoh Ayimba, Yaovi Ameyapoh, Nakpane Fankibe
Keywords
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