The Antimicrobial Activity of Antiseptics on Clinical Strains of Microorganisms Contaminating Military Wounds of Limbs
Journal Title: Український журнал медицини, біології та спорту - Year 2017, Vol 8, Issue 6
Abstract
The article deals with the role of antiseptics in military wounds treatment connected with the emergence of a significant number of multi–drug resistant strains of microorganisms. Local application of antiseptics for prevention and treatment of wounds’ infections looks promising. The purpose of the study was to evaluate the efficiency of modern antiseptics against microorganisms allocated in combat injuries. Sensitivity of microorganisms to antiseptics (Decamethoxin, Benzalkonium Chloride, Miramistin, Chlorhexidine Digluconate, Polyhexamethylene Guanidine, Octenidine, and Iodine–Povidone Hydrogen Peroxide) was examined by serial double dilutions. Minimal bactericidal concentration was used for assessment of sensitivity to the drugs. The qualitative slurry test determined the exposure time needed for the complete destruction of the clinical strains. Tested drugs concentration was sufficient to achieve stagnation effect. Susceptibility levels of investigated microorganisms to antiseptics were significantly lower than antiseptics concentrations usually used in practice. The slurry qualitative tests have shown that any of the antiseptics can lead to the complete destruction of microbial cultures by increasing the time of direct exposure. In order to achieve an effective impact on microorganisms it is necessary to use techniques that provide sustained release of the antiseptic in a wound.
Authors and Affiliations
V. Kondratiuk
Keywords
Related Articles
- EP ID EP276263
- DOI -
- Views 106
- Downloads 0
CHANGES OF INDICATORS OF SEROTONINERGIC AND NITROXIDERGIC SYSTEMS AT THE STAGES OF DEVELOPMENT OF THE GENERAL ADAPTATION SYNDROME IN PATIENTS WITH ISCHEMIC STROKE
The general adaptation syndrome that occurs in patients with ischemic stroke in response to hypoxic damage to neurons of the brain is characterized by a combination of stereotyped reactions that provides the body to the...
Dynamics of Indexes of White Blood Cells during Experimental Biliary Peritonitis
One of the most serious diseases of the abdominal cavity organs is biliary peritonitis. The aim of the research is to study the leukocyte index of intoxication and the number of leukocytes in experimental gallstone in an...
ПОКАЗНИКИ ПРО-/АНТИОКСИДАНТНОЇ СИСТЕМИ У НИРКАХ ЩУРІВ ЗА УМОВ CОЛЬОВОГО НАВАНТАЖЕННЯ НА ТЛІ ТОКСИЧНОГО УРАЖЕННЯ СУЛЕМОЮ
На білих нелінійних щурах-самцях з токсичним отруєнням сулемою та при сольовому навантаженні було досліджено процеси пероксидного окиснення макромолекул, вивчено зміни антиоксидантних ферментів у різних відділах нирок. З...
Estimation of Carcinogenic Risks of Drinking Water Consumption in the Cities of Dnipro and Kamyan'sk
To provide 80% of the population of Ukraine with drinking water, they use superficial water sources of commercial drinking water supply. Thus, the water quality has deteriorated in recent years. The most significant amon...
ANTIPHOSPHOLIPID SYNDROME: CLINICAL FEATURES AND GENETICS OF THROMBOTIC MANIFESTATIONS
Pathogenetic mechanisms of the development of antiphospholipid syndrome (APS) are presented in the article, which is the basis for the development of clinical manifestations and laboratory markers of APS. The modern lite...