The Antioxidant and Hepatoprotective Activities of Two Tea Polysaccharides
Journal Title: Journal of Antioxidant Activity - Year 2015, Vol 1, Issue 2
Abstract
In the present study, we investigated the chemical compositions, in vitro antioxidant and in vivo hepatoprotective activities of two tea polysaccharides (TPS), which were extracted from two different tea cultivars, Yingshuang (Camellia Senesis, T01) and Yunnan Dayezhong (Camellia Senesis, T09). Compared with T09-TPS, T01-TPS had lower contents of neutral sugar, protein, uronic acid and polyphenol. However, T01-TPS showed stronger scavenging abilities for transient free radicals of hydroxyl radical and superoxide anion radicals and lipid peroxidation inhibition effect, but weaker scavenging ability for stable free radical of DPPH. For hepatoprotective activity in vivo, the results demonstrated that both T01-TPS and T09-TPS could significantly prevent the increase of serum alanine aminotransferase and, aspartate aminotransferase levels, decrease the liver index, reduce the formation of malonydialdehyde and enhance the activities of superoxide dismutase, glutathione peroxidase and peroxidase in carbon tetrachloride-induced liver injury mice. These results suggest that T01-TPS and T09-TPS have potent antioxidant and hepatoprotective activities.
Authors and Affiliations
Yutao Shi, Yujie Ai, Yuqiong Chen, Dejiang Ni, Zhi Yu
Keywords
Related Articles
- EP ID EP426376
- DOI 10.14302/issn.2471-2140.jaa-17-1541
- Views 170
- Downloads 0
Methionine and Antioxidant Potential
Methionine (Met) is a nutritionally essential amino acid and has been widely demonstrated to improve cellular oxidative balance and mediate oxidative stress. Met targets reactive oxygen species (ROS) directly by being ox...
The Assessment of Alchornea Cordifolia Activity in Aflatoxicosis Reduction in Rat.
Introduction: Aflatoxins are cytotoxic andserve as one of the key risk factors of hepatocellular carcinoma. Currently, plants and extract are widely used as potential scavenging substances for the detoxification of myco...
The Total Antioxidant Capacity of Foods: A Reappraisal. Application to Commercial Orange Juices
Since a few years, more and more attention has been specifically given to dietary antioxidants as agents promoting health and preventing the incidence of diseases. As part of these efforts, analytical methods and assays...
Investigation on Phytochemical and Antioxidant Activity of the Plant Murraya koenigii Linn (Curry leaf) in Rajshahi, Bangladesh
The use of herbal medicine is becoming popular day by day due to toxicity and side effects of allopathic medicines. Considering the medicinal importance of the plant Murraya koenigii Linn (Curry leaf), the antioxidant ac...
The Antioxidant and Hepatoprotective Activities of Two Tea Polysaccharides
In the present study, we investigated the chemical compositions, in vitro antioxidant and in vivo hepatoprotective activities of two tea polysaccharides (TPS), which were extracted from two different tea cultivars, Yings...