The assessment of the impact of thrombocytopenia symptoms on the patients’ daily activities with the use of TSIDAV vignette
Journal Title: JOURNAL OF HEALTH POLICY & OUTCOMES RESEARCH - Year 2016, Vol 9, Issue 1
Abstract
Objective: Assessment of the impact of thrombocytopenia symptoms on patients’ daily activities using vignettes. Methods: Vignettes were used to collect information from adult patients and children’s caregivers in order to assess the impact of thrombocytopenia symptoms on patients’ daily activities. Each vignette consisting of two parts aimed at collecting qualitative information about major health problems related to thrombocytopenia symptoms and at measuring the intensity of the symptoms’ impact on daily activities in a quantitative way. Descriptive part collected patients’ qualitative information about symptoms influencing their daily functioning or those bothering them the most. Quantitative part using Likert scale assessed the impact of specific symptoms on patients’ lives. Results: We collected 61 questionnaires from 31 women, 17 men, 13 children’s caregivers. Among men the biggest impact on activities was observed in relation to petechiae and easy bruising (both symptoms were declared as significant by 29% of respondents). 68% women considered skin and mucosa petechiae, 65% indicated easy bruising and 52% bleeding from gums and nose as having significant impact on daily activities. 62% of parents or caregivers believed that petechiae and mucosa had significant impact on the performance of the children’s daily activities, same significance was referenced to easy bruising (54%) and bleeding from gums and nose (42%). Conclusions: Thrombocytopenia symptoms influence patients’ daily activities and the most frequently mentioned symptoms influencing those across all groups were petechiae and easy bruising. According to the calculated vignettes values the highest impact on daily activity of the symptoms was indicated for children.
Authors and Affiliations
Monika Szkultecka-Dębek, Mariola Drozd, Małgorzata Nowakowska, Marta Bem, Nina Wiśniewska, Joanna Mazur
Nutritional management in patients with gastrointestinal tumors in the surgical department
The last quarter of 25 years is undoubtedly a milestone in clinical nutrition in Poland. The current years have shown the growing importance of this medical area, which is now a component of many therapies. A better nour...
Assessment of quality and clinical significance of endpoints in cancer immunotherapy
This review describes available immunotherapeutic agents approved for the treatment of prostate cancer (sipuleucel-T), advanced melanoma (ipilimumab, pembrolizumab, nivolumab) and NSCLC (nivoluamb) and underline that the...
Real World Evidence (RWE) and Orphan drug policies in selected Central and Eastern European (CEE) Countries
The rationale for the initial project performed in the Central and Eastern European countries (CEE) was to assess and to share information from the region regarding drug policies. With this special cross countries compar...
Medical registries in perspective of the new EU’s legal framework of personal data protection - selected issues
Keeping medical registries is inextricably linked with the processing of personal data, which often belong to the most sensitive sphere of privacy of every individual. Creating a comprehensive and complete legislation in...
RWE in Europe – An Analysis
Background – This paper outlines findings from four roundtable discussions involving a number of stakeholders. They aimed to improve understanding of the use of real world evidence (RWE) across Europe. They focused on th...