The Association amongst ‘Triple Negative’ Breast Cancers, Lymph Node Metastasis, Disease Free and Overall Survival
Journal Title: Journal of Cancer Sciences - Year 2015, Vol 2, Issue 1
Abstract
Triple negative’ breast cancer (TNBC) has fewer specific targets for systemic therapy. We hypothesized that patients with TNBC have an increased incidence of sentinel lymph node (SLN) metastases and decreased disease-specific and overall survival.
Authors and Affiliations
S. David Nathanson
The Association amongst ‘Triple Negative’ Breast Cancers, Lymph Node Metastasis, Disease Free and Overall Survival
Triple negative’ breast cancer (TNBC) has fewer specific targets for systemic therapy. We hypothesized that patients with TNBC have an increased incidence of sentinel lymph node (SLN) metastases and decreased disease-spe...
N-Hydroxy-6-(5-Nitro-Naphtalimide)-Hexanamide Inhibits Lysine Deacetylation, Mitigates Angiogenesis and Reduces Tumor Growth
In this report, we present a novel histone deacetylase inhibitor (HDACi) (N-Hydroxy-6-(5-nitro-naphtalimide)-hexanamide: ES8) that efficiently inhibits angiogenesis in relevant ex vivo models (Human umbilical vein endoth...
Microarray Based Genotyping: A Review
Microarray technology has become a very popular tool in the realm of current molecular biology tools, and combined with the increasing knowledge and accuracy gained by advances in human genome sequencing, this technique...
White Adipose Tissue Browning and Cancer Cachexia
Cachexia or wasting syndrome is often seen in cancer patients. Over half of the patients suffer from this condition although the incidence varies from tumor types. Symptoms of cancer cachexia include progressive weight l...
Massive Intra-Tumor Hemorrhage during Induction Chemotherapy in Neuroblastoma: A Case Series Report
We describe 5 children with high risk neuroblastoma (NB) who, during the induction phase of therapy, were admitted with circulatory shock because of massive intra-tumor bleeding. Patient’s intensive supportive care with...