The Association amongst ‘Triple Negative’ Breast Cancers, Lymph Node Metastasis, Disease Free and Overall Survival
Journal Title: Journal of Cancer Sciences - Year 2015, Vol 2, Issue 1
Abstract
Triple negative’ breast cancer (TNBC) has fewer specific targets for systemic therapy. We hypothesized that patients with TNBC have an increased incidence of sentinel lymph node (SLN) metastases and decreased disease-specific and overall survival.
Authors and Affiliations
S. David Nathanson
Gemcitabine-Capecitabine Chemotherapy Plus Intra- Arterial Epirubicin-Cisplatin in Pancreatic Cancer Patients after FOLFIRINOX First Line Chemotherapy: A Retrospective Analysis
Background: Most pancreatic cancer patients have disease recurrence/progression within 6 months from firstline chemotherapy end. Today, there is no a standard of care of second-line therapy. Materials (patients) and me...
White Adipose Tissue Browning and Cancer Cachexia
Cachexia or wasting syndrome is often seen in cancer patients. Over half of the patients suffer from this condition although the incidence varies from tumor types. Symptoms of cancer cachexia include progressive weight l...
High Dose Vitamin C and Low Dose Chemo Treatment
Research has shown that intravenous high dose vitamin C in cancer therapy cannot be dismissed but that it warrants further investigation. Recent studies have made more inroads into the understanding of the role of vitami...
Rectifying the Epigenetic Field Defect in Gastric Carcinogenesis
Gastric cancer is undoubtedly a fatal malignancy worldwide with high incidence and dismal prognosis. Its formation and development can be driven by genetic defects, dietary factors, alcohol consumption, viral infection,...
HTLV-I Tax-Mediated Inactivation of Cell Cycle Checkpoints and DNA Repair Pathways Contribute to Cellular Transformation: “A Random Mutagenesis Model”
To achieve cellular transformation, most oncogenic retroviruses use transduction by proto-oncogene capture or insertional mutagenesis, whereby provirus integration disrupts expression of tumor suppressors or proto-oncoge...