The Association Between Whole Blood Viscosity and Obstructive Coronary Artery Disease in Patients with Premature Acute Coronary Syndrome

Journal Title: Journal of Ankara University Faculty of Medicine - Year 2019, Vol 72, Issue 3

Abstract

Objectives: Acute Coronary syndrome (ACS) in young adults is relatively rare, but it is in an increasing trend in recent years. Few data on ACS in young adults are available in the literature, especially regarding risk factors. In the current study, the importance of whole blood viscosity (WBV) was evaluated in patients with newly diagnosed premature ACS. Materials and Methods: A total of 713 patients (469 male, mean age: 38.9±2.4 years) were included. The study population was divided into two groups. The first group included 357 patients who presented with newly diagnosed premature ACS (aged ≤45 years and were found to have critical lesions in their coronary arteries, while the control group consisted of 356 patients who were age and gender-matched controls and were found to have normal coronary arteries after elective coronary angiography. WBV was calculated according to the Simone’s formula at both high and low shear rates and compared between two groups with other traditional risk factors. Results: Patients with premature ACS were found to have significantly increased WBV values compared to controls. Univariate and multivariate logistic regression analysis revealed that the WBV at both shear rates was an independent predictor for the presence of critical CAD after adjusted for other traditional cardiovascular risk factors. Conclusion: Patients with increased WBV values were at greater risk for the presence of premature ACS with critical lesions compared with the control group.

Authors and Affiliations

Bahar Tekin Tak, Firdevs Ayşenur Ekizler, Serkan Çay, Habibe Kafes, Elif Hande Özcan Çetin, Nedret Ülvan, Özcan Özeke, Fırat Özcan, Serkan Topaloğlu, Dursun Aras

Keywords

Related Articles

Differentiation of Human Leukemia Monocyte Cells to Macrophage-Like Cells with Phorbol- 12-Myristate-13-Acetate

Objectives: In this study, it was aimed to evaluate appropriate model of application time and dosage of Phorbol-12-Myristate-13-Acetate (PMA) to get activated macrophages from monocytic cell line THP-1 cells. The differe...

Thoracoscopic Lobectomy and Segmentectomy in Children

Objectives: In the last decade, video-assisted thoracoscopic surgery (VATS) is gaining broad popularity in pediatric surgery. The purpose of this study is to analyze the clinical and histopathological results of VATS in...

The Protective Effect of Coenzyme Q10 on the Renal Ischemia Reperfusion Induced Liver Injury

Objectives: The aim of this study was to show the efficacy of coenzyme Q10, known as anti-oxidant with anti-inflammatory properties, in liver damage after renal ischemia-reperfusion (RIR). Materials and Methods: For thi...

Etiological and Demographic Characteristics of Patients with Vestibular Symptoms, Retrospective Analysis

Objectives: Vertigo and dizziness are among the most common causes of medical consultation, with an estimated prevalence of 20% and 30%. Vertigo and/or dizziness are non-specific symptoms that can be caused by various di...

Thoracic Intradural Extramedullary Epidermoid Tumor: Two Rare Cases

Intradural epidermoid tumors of the spinal cord are commonly associated with spinal cord dysraphism or invasive procedures. The spinal epidermoid tumor, frequently located intradural extramedullary region, is typically f...

Download PDF file
  • EP ID EP684780
  • DOI 10.4274/atfm.galenos.2019.74936
  • Views 153
  • Downloads 0

How To Cite

Bahar Tekin Tak, Firdevs Ayşenur Ekizler, Serkan Çay, Habibe Kafes, Elif Hande Özcan Çetin, Nedret Ülvan, Özcan Özeke, Fırat Özcan, Serkan Topaloğlu, Dursun Aras (2019). The Association Between Whole Blood Viscosity and Obstructive Coronary Artery Disease in Patients with Premature Acute Coronary Syndrome. Journal of Ankara University Faculty of Medicine, 72(3), -. https://europub.co.uk/articles/-A-684780