The association of serological tests and anemia in celiac disease
Journal Title: UNKNOWN - Year 2018, Vol 1, Issue 2
Abstract
Aim: Celiac disease (CD) is a common immune-mediated enteropathy caused by gluten. These patients may apply with many different clinical forms. The aim of this study is to determine the association of serological tests and type of anemia in CD. Methods: Totally117 biopsy proven CD patients aged between 1-17 years were included. Serological and hematological parameters of all patients were studied. Results: Anemia was identified in 71 (60.7%) cases. Patients with anemia were diagnosed earlier than other patients (5.2±4.5 vs. 15.3±33.8 years, p=0.012). Among CD patients with anemia 39 (54.9%) were having iron deficiency, 22 (30.9%) were having folate deficiency and 10 (14%) were having vitamin B 12 deficiency. In patients with tissue transglutaminase (tTG) seropositivity serum iron levels and ferritin levels were significantly lower compared to anti-gliadin antibody (AGA) or anti-endomysium antibody (EMA) seropositivity (35±23.5 vs. 57.5±33.3, p=0.007 and 12.4±21.9 vs. 24.2±18.5, p=0.026, respectively). Low serum folate levels were more frequent in the presence of tTG seropositivity compared with AGA+EMA seropositivity (81.8% vs. 25%, p=0.015). Conclusions: Anemia is an important cause of admission in CD. These patients are diagnosed earlier as a result of anemia. Alone tTG seropositivity is more valuable to demonstrate anemia associated with iron or folate deficiencies.
Authors and Affiliations
Mervan Bekdas, Fatih Unal
Keywords
Related Articles
- EP ID EP498051
- DOI 10.30714/j-ebr.2018237495
- Views 156
- Downloads 0
Thyroid fine needle aspiration reporting rates and outcomes before and after Bethesda implementation: A single-center experience over 8 years
Aimː To evaluate data from our hospital system before and after the implementation of the Bethesda System for Reporting Thyroid Cytology (TBSRTC) and comparison of our data with the previously published studies. Methods:...
The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study
Aim: This study investigated the effect of antiepileptic drug monotherapy on cognitive functions in pediatric epilepsy patients. Methods: 98 recently diagnosed epilepsy patients aged 6-16 years were included. All pat...
Surgical treatment of inguinal hernia: Our experience
Aim: In present retrospective analysis, we aimed to evaluate the treatment results of subjects with inguinal hernia whom underwent surgical repair. Methods: Surgical treatment of inguinal hernia for last 7 years have be...
Is it necessary to perform an endometrial sampling prior to hysterectomies for benign conditions?
Aim: Hysterectomy is one of the most prevalent surgical intervention in gynecological field. This study concerns the requirement and necessity of an endometrial sampling to exclude an unpredictable uterine malignancy ris...
Evaluation of the resistance patterns of Mycobacterium tuberculosis complex strains to antituberculous drugs
Aim: To determine the resistance profile of Mycobacterium tuberculosis complex (MTBC) strains to first-line antituberculous drugs. Methods: A total of 138 patients with MTBC growth from 2008-2018 were evaluated retrospec...