The Biochemistry and Clinical Significance of D-Dimer
Journal Title: International Journal of Health & Medical Research - Year 2024, Vol 3, Issue 10
Abstract
D-dimer, product degradation of fibrin, belongs to the most sensitive and specific markers in the diagnostics of thrombotic disorders, mainly acute PE and DVT. This leads to its measurement because of the high sensitivity in ruling out these conditions, thus reducing unnecessary imaging and improving patient management. The importance of D-dimer has been repeatedly said in various studies, notably during the COVID-19 pandemic, where it has been noted as an essential biomarker in the assessment of thrombotic complications, treatment strategy, and prognostic aspects of the patient. This literature review paper covers basic principles and measurements of D-dimer because of up-to-date knowledge on its clinical applications, limitations, and directions for potential future research.
Authors and Affiliations
Umalbaneen Hussain Ismael
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