THE CHANGES IN THE UTERUS OF OVAREICTOMIZED MICE IN RESPONSE TO PLUMERIA ACUMINATA AIT STEM EXTRACT
Journal Title: ASIAN JOURNAL OF NATURAL & APPLIED SCIENCES - Year 2016, Vol 5, Issue 3
Abstract
Objective: The primary objective of this study is to assess the effect of methanolic stem extract of Plumeria acuminata Ait. on the uterus and estrogenic/antiestrogenic potency of the plant, which are traditionally used by the Mising tribes of Assam, India for curing different reproductive ailments. Method: Extracts of the plant was prepared and given to ovariectomized mice at two dose level (200mg/kg and 400mg/kg orally). Evaluations were made based on the uterotrophic assay by observing the amount of protein, uterine wet weight, histopathological examination and serum cholesterol label. Results: The extract was found to have significant changes in the wet uterine weight and in the other biochemical parameters. Similarly the histological examination of the uterus also reveals the similar effect of the plant extract though there was non-significant change in the body weight. Conclusion: The results suggest that the stem extract of Plumeria acuminata Ait. have significant estrogenic property suggesting for a possible contraceptive activity which is consistent with the literature report on folk medicine of the plant used by the missing tribe of this region.
Authors and Affiliations
T. C. Taid, R. C. Rajkhowa, J. C. Kalita
Keywords
Related Articles
- EP ID EP204429
- DOI -
- Views 105
- Downloads 0
A STUDY OF REQUIREMENTS VALIDATION WITH UML
he major concern of requirements validation is to evaluate software system at the end of the software development process to ensure compliance with the software requirements. Among the various b...
FACTORS CAUSING MENTAL RETARDATION
Mental Retardation (MR) is a heterogeneous group of disorders characterized by a significant impairment of cognitive and development due to abnormalities in the structure or function of brain. Mentally Retarded persons h...
USING THE KNOWLEDGE-BASED SYSTEM (KBS) TO IMPROVING SYSTEM FOR CRACK DIAGNOSIS IN R.C COLUMN
Over the last several years, many concrete structural have been constructed. For safety in concrete structure, periodic inspection has been conducted using many testing technologies and techniques. However, these...
TRANSIENT ENHANCEMENT OF NIGERIAN GRID SYSTEM USING OPTIMALLY TUNED UPFC BASED ON SMALL POPULATION PARTICLE SWARM OPTIMIZATION
Transient and dynamic stability considerations are among the most important issues in the reliable and efficient operation of power systems. Flexible AC Transmission Systems (FACTS) devices produced more flexibil...
STRENGTH OF A CERAMIC AT HIGH TEMPERATURES UNDER DIAMETRAL COMPRESSION
A novel design is presented for the high temperature compression testing of ceramic discs up to temperature of 1300oC. Two proprietary silicon nitrides containing magnesia (MgO) and a mixture of magnesia and yttr...