THE CHEMICAL COMPOSITION AND THE ANTIMICROBIAL PROPERTIES OF THE ESSENTIAL OIL EXTRACTED FROM THE LEAVES OF TEUCRIUM CAPITATUM L.
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2017, Vol 10, Issue 2
Abstract
Objective: In the framework of the search for new biological molecules, an ethnobotanical study has been carried out in the region of El Hajeb in Morocco in the interest of will select the data ethnopharmacological on medicinal and aromatic plants and on the découveres new principles assets. On the basis of a questionnaire prepared, a survey was conducted of the local population where we find a close relation which exists between the plant species described in the said region and the different types of diseases affecting the human being; six plants have been chosen to evaluate the antifungal activity of essential oils against the bacterial strain (Staphylococcus aureus, and on two yeasts: Candida albicans and Candida glabrata, which are the most frequently identified in clinical specimens, a mold: Aspergillus niger, and 5 dermatophytes: Microsporum canis, Microsporum gypseum, Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum.Methods: The extraction of essential oils was carried out by steam distillation in a clevenger-type apparatus. The antimicrobial activity was determined by the disc diffusion method. The chromatographic analysis of HE five plants was performed with a gas chromatograph (GC) type Hewlett-Packard (6890) coupled to a mass spectrometer (HP5973).Results: The results show that the essential oil of Teucrium capitatum L. has a large antimicrobial activity vis-a-vis other plants. Therefore, an identification of their chemical composition is necessary to identify the active molecules based on the analysis GC-only and coupled to mass spectrometry (GC-MS). The essential oil of the plant of T. capitatum L. of the region of El Hajeb (Morocco) was extracted to the study its performance, its chemical composition, and its property antibacterial and antifungal. The average content in essential oil of the leaves of this species is approximately2% (wt.) of the total weight of dry matter. The chromatographic analysis showed the profiles, and the rates of the different components compared to the available standards, as function of the retention time by ascending order, four compounds were identified by GC and GC/MS as the main compounds of this oil: Endo-borneol (33%), naphthalene, 1, 2, 3, 5, 6, 8a-hexahydro-4,7-dimethyl-1-(1-methyl ethyl)-, (1s-cis)-(19.63%), bronyle acetate (15.56%), alpha-terpineol (11.96%), bicyclo[3.1.0]hexan-3-ol, 4-methyl-1-(1-methylethyl)-(10.94%) among other 21 compounds.Conclusion: This study allows, once again, the development of the exploitation of the essential oils in the areas, pharmaceutical and medicines and works the doors of the exploitation of these plants in the pharmaceutical market. Keywords: Teucrium capitatum L., Ethnobotanical study, Antifungal activity, Chromatography.
Authors and Affiliations
Jalila El Amri, Khalid El Badaoui, Zoubida Haloui
Keywords
Related Articles
- EP ID EP605411
- DOI 10.22159/ajpcr.2017.v10i2.14504
- Views 84
- Downloads 0
THERAPEUTIC POTENTIAL AND IN VITRO ANTHELMINTIC ACTIVITY OF RIDGE GOURD FRUIT
Objective: The objective of the study was to evaluate the therapeutic potential and in vitro anthelmintic activity of ridge gourd fruit (Luffa acutangula) against Indian earthworms. Methods: For anthelmintic activity ag...
ANTIBIOTIC PRESCRIBING PROFILE FOR PEDIATRIC AT THE PHARMACY OF MEDAN CITY IN 2016
Objective: The aim of this study was to determine antibiotics prescribing profile for pediatric in Medan, Sumatra Utara (Indonesia) in 2016.Methods: This study was using a retrospective cross-sectional method study which...
DESIGNING A VACCINE FOR CANCER: A LOOK INTO DENDRITIC CELL CANCER VACCINE
The fundamental premise behind clinical approaches for dendritic cell-mediated immunization in cancer is that the limiting defect in natural antitumor immunity is at the level of antigen presentation. In contrast to vacc...
HOMOCYSTEINE: A NEWER AND NOVEL INDEPENDENT RISK FACTOR AND CARDIAC MARKER FOR ACUTE MI
Objective: The objective of this study was to estimate homocysteine levels in myocardial infarction (MI) patients (troponin-T positive) and normal healthy individuals (troponin-T negative) subsequently to make comparison...
MAJOR BIOACTIVE TRITERPENOIDS FROM GANODERMA SPECIES AND THEIR THERAPEUTIC ACTIVITY: A REVIEW
Ganoderma a traditional Chinese medicine popularly used for complementary cancer therapy and longevity for centuries. The vast amount of study has been performed on the medicinal properties of Ganoderma lucidum. G. lucid...