THE CHEMICAL COMPOSITION AND THE ANTIMICROBIAL PROPERTIES OF THE ESSENTIAL OIL EXTRACTED FROM THE LEAVES OF TEUCRIUM CAPITATUM L.
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2017, Vol 10, Issue 2
Abstract
Objective: In the framework of the search for new biological molecules, an ethnobotanical study has been carried out in the region of El Hajeb in Morocco in the interest of will select the data ethnopharmacological on medicinal and aromatic plants and on the découveres new principles assets. On the basis of a questionnaire prepared, a survey was conducted of the local population where we find a close relation which exists between the plant species described in the said region and the different types of diseases affecting the human being; six plants have been chosen to evaluate the antifungal activity of essential oils against the bacterial strain (Staphylococcus aureus, and on two yeasts: Candida albicans and Candida glabrata, which are the most frequently identified in clinical specimens, a mold: Aspergillus niger, and 5 dermatophytes: Microsporum canis, Microsporum gypseum, Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum.Methods: The extraction of essential oils was carried out by steam distillation in a clevenger-type apparatus. The antimicrobial activity was determined by the disc diffusion method. The chromatographic analysis of HE five plants was performed with a gas chromatograph (GC) type Hewlett-Packard (6890) coupled to a mass spectrometer (HP5973).Results: The results show that the essential oil of Teucrium capitatum L. has a large antimicrobial activity vis-a-vis other plants. Therefore, an identification of their chemical composition is necessary to identify the active molecules based on the analysis GC-only and coupled to mass spectrometry (GC-MS). The essential oil of the plant of T. capitatum L. of the region of El Hajeb (Morocco) was extracted to the study its performance, its chemical composition, and its property antibacterial and antifungal. The average content in essential oil of the leaves of this species is approximately2% (wt.) of the total weight of dry matter. The chromatographic analysis showed the profiles, and the rates of the different components compared to the available standards, as function of the retention time by ascending order, four compounds were identified by GC and GC/MS as the main compounds of this oil: Endo-borneol (33%), naphthalene, 1, 2, 3, 5, 6, 8a-hexahydro-4,7-dimethyl-1-(1-methyl ethyl)-, (1s-cis)-(19.63%), bronyle acetate (15.56%), alpha-terpineol (11.96%), bicyclo[3.1.0]hexan-3-ol, 4-methyl-1-(1-methylethyl)-(10.94%) among other 21 compounds.Conclusion: This study allows, once again, the development of the exploitation of the essential oils in the areas, pharmaceutical and medicines and works the doors of the exploitation of these plants in the pharmaceutical market. Keywords: Teucrium capitatum L., Ethnobotanical study, Antifungal activity, Chromatography.
Authors and Affiliations
Jalila El Amri, Khalid El Badaoui, Zoubida Haloui
Keywords
Related Articles
- EP ID EP605411
- DOI 10.22159/ajpcr.2017.v10i2.14504
- Views 109
- Downloads 0
SCABIOSA COLUMBARIA: A REVIEW OF ITS MEDICINAL USES, PHYTOCHEMISTRY, AND BIOLOGICAL ACTIVITIES
Scabiosa columbaria is a perennial herb widely used as herbal medicine throughout its distributional range in tropical Africa, Asia, and Europe. This study is aimed at providing a critical review of the biological activi...
A STUDY ON FORMULATION AND ACCEPTABILITY OF ANTI-COLD MOCKTAILS WITH VITAMIN C ENRICHED INGREDIENTS
Objectives: Common cold is a widespread respiratory infection among all age groups. This creates a great nuisance and discomfort making a person feels ill. Common cold can also be treated with home-made remedies. The stu...
MEDICINAL HERBS AND PHYTOCHEMICALS USED IN THE TREATMENT OF DEPRESSION: A REVIEW
Depression is a condition of no mood and loss of interest in any activity that can diminish a person’s thinking, conduct, tendencies, emotional state, and a sense of well-being. Although there is a conventional class of...
ASSESSMENT OF ANTIOXIDATIVE AND AMELIORATIVE POTENTIAL OF AQUEOUS EXTRACT OF LEAVES OF THUJA ORIENTALIS (PLATYCLADUS ORIENTALIS [L.])
Objective: The main objective of the present study is to assess the antioxidative and attenuating potential of aqueous extract of leaves of Thuja orientalis (AET) against the genotoxicity induced by chlorpyrifos (CPF) (O...
DIFFERENCES VALUE OF BLOOD UREA NITROGEN AND CREATININE SERUM IN CERVICAL CANCER SQUAMOUS CELL STADIUM IIB-IIIB BEFORE AND AFTER CHEMOTHERAPY PACLITAXEL CISPLATIN FOR SIX CYCLE IN SANGLAH GENERAL HOSPITAL DENPASAR BALI
Objective: The combination of paclitaxel-cisplatin regimen is one of the chemotherapy regimens used at Sanglah General Hospital, Denpasar. Cisplatin is a potent chemotherapeutic agent, but the nephrotoxic effects of cisp...