The clinical course of abscesses and soft tissue phlegmon in HIV-infected patients
Journal Title: Хірургія України - Year 2018, Vol 0, Issue 3
Abstract
The aim — to study the features of the clinical course of abscesses and soft tissue phlegmon in HIV‑infected patients. Materials and methods. The clinical course analysis of the abscesses and soft tissues phlegmon in 90 HIV‑infected patients (main group) who were on treatment at the Surgery and Proctology Department for the period from 2013 to 2017 was done. The comparison group consisted of 90 patients with abscesses and soft tissues phlegmon without concomitant HIV infection. The average age of patients was 31.0 ± 1.2 years. The abscesses and phlegmons localization were shoulder, forearm, gluteal region, inguinal region, thigh, shin. Clinical criteria, such as the fever response expression and purulent discharge duration, wound cleansing term were used to evaluate the clinical course of the postoperative period. Immunological status of patients was also investigated. Results and discussion. When analyzing the clinical picture, it was found that after the opening of the abscess and adequate drainage, the duration and severity of fever response expression, the purulent discharge from the wound and the time of wound clearance compared to those without HIV infection were statistically significantly higher in patients with HIV infection. In patients with HIV infection, a marked change in immunoregulation in favor of the predominance of T‑suppressors and a decrease in the number of T‑helpers revealed. Therefore, immunocorrection with retroviral drugs in accordance with existing protocols is indicated to these patients. Conclusions. The clinical course of abscesses and phlegmon in HIV‑infected patients compared with a group of patients without HIV infection is characterized by longer periods of purulent discharge and wound cleansing, hospital stay, especially in HIV‑infection of III — IV stages, which is confirmed by immunologic disorders, level of T‑helpers, requires a longer and more intensive both general and local treatment in combination with retroviral therapy.
Authors and Affiliations
Iu. O. Shylenko, Ia. P. Feleshtynskyi, V. V. Smishchuk, T. V. Stepchenkova
Keywords
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- EP ID EP416311
- DOI 10.30978/SU2018-3-91
- Views 149
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