The Clinical, Diagnostic, and Therapeutic Characteristics of 22 Male Patients with Breast Cancer
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2016, Vol 13, Issue 12
Abstract
Aim: The aim of this study is to evaluate the clinicopathological, diagnostic, and therapeutic features of male breast cancer. Study Design: This is a retrospective clinical study. Methodology: Twenty-two male patients who underwent surgery for breast cancer in a tertiary reference hospital in Ankara between 2010 and 2015 were included in this retrospective study. Patient characteristics, clinical findings, diagnostic and therapeutic features were recorded. Results: Among the 22 patients with a mean age of 59.6 years, 3 (13.6%) had a family history of BC. Painless breast mass was the most common (95.5%) presenting symptom. Hypoechoic breast mass with irregulary margins was the most frequent sonographic finding (90.9%) while mammography revealed asymmetric density or poorly defined mass in the majority of cases (75%). Modified radical mastectomy was the most performed surgical type (n= 21, 95.5%). In one patient, simple mastectomy was performed for a diagnosis of ductal carcinoma in situ. Twelve (54.5%) patients received adjuvant chemotherapy while 3 (13.6%) cases had radiation therapy. Hormonal therapy was given to 17 (77.2%) patients with receptor positivity. Median follow-up time of the patients was 31.2 months, and 3 recurrences was observed. Conclusion: The incidence of male breast cancer has been increased in the recent years. Since the management of male breast cancer is still based on the rules of female breast cancer, large scale clinical studies are urgently needed to develop an international guideline for of this rare cancer.
Authors and Affiliations
Serdar Gökay Terzioğlu, Murat Özgür Kiliç, Gül Dağlar
Effect of Anterıor and Posterıor Capsular Polıshıng on the Rate of Posterıor Capsule Opacıfıcatıon
Aim: To analyze whether anterior and posterior capsule polishing after lens cortex cleaning done by phacoemulsification has any effect on the rate of posterior capsule opacification (PCO). Study Design: Randomized contro...
The Rabbit Model of Femoral Bone Defects: Steps to Overcome Potential Pitfalls
Aims: To identify the potential pitfalls and indicate procedures to prevent them, during the evaluation of biomaterials for orthopaedic and craniofacial research in the New Zealand White (NZW) rabbit animal model of femo...
Pseudo Meig's Syndrome: An Unusual Presentation
Aim: To describe the radiological findings in a case of pseudo Meig’s syndrome with rare association of pericardial effusion. Presentation of Case: We report a case of pseudo Meig's syndrome who also had pericardial effu...
Optical Biopsy with Probe-based Confocal Laser Endomicroscopy for Prediction of Residual Barrett’s Esophagus after Complete Radiofrequency Ablation (RFA)– A Pilot Study
Introduction: Radiofrequency ablation (RFA) of Barrett’s esophagus (BE) is associated with a high rate of complete eradication and a reduced risk of disease progression. Nevertheless, recent data indicate that about one...
The Role of Transglutaminase 2 (TG2) in Definition of Cancer Hallmarks
Over the past three decades, TGM2, a stress-responsive gene encoding transglutaminase 2 (TG2) has been identified as one of the several genes that may be involved in carcinogenesis and cancer physiology. TG2 is a pleiotr...