The Clinical, Neurophysiological, Radiological and Neuropathological Study of Hansen’s Disease in Hamidia Hospital Bhopal
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 6
Abstract
Introduction: The peripheral nerve injury has been associated with physical disability and is the most serious complication of leprosy. The diagnostic tests including nerve conduction velocity testing and ultrasound of ulnar nerve may reveal the defect in the nerve before the disease become clinically more apparent. Material and methods: The study was an observational study with a total of 50 patients. Patients who were diagnosed cases of leprosy are registered in this study based on inclusion and exclusion criteria. Results: The most frequent clinical forms were borderline tuberculoid (46%) and indeterminate (14%) and borderline number (14%). Regarding the degree of disability 78% had leprosy grade 0, 18% had grade 1 and 4% had grade 2. With nerve conduction study, the changes in sensory nerve conduction were more pronounced. high resolution ultrasonography of the ulnar nerve at elbow was done showed nerve thickening in 54% cases and 10% of the patients showed atrophic changes. Out of the 26 patients who undergone sural nerve biopsy acid fast bacilli was found in 7 patients; mononuclear infiltrates in 24 patients, thickness of endo-peri-epi-neurium was found in 5 patients. Conclusions: Sonography and electrophysiology were complementary for identifying ulnar nerve neuropathy in patients with leprosy, this reinforces the role of sonography in the investigation of leprosy ulnar neuropathy. Nerve conduction testes can reveal nerve involvement before the disease became clinically apparent.
Authors and Affiliations
T. N. Dubey, Neelesh Damor
Keywords
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