THE COMPARATIVE STUDY TO EVALUATE THE EFFECTIVENESS OF DEXMEDETOMIDINE VERSUS PROPOFOL INTRAVENOUS INFUSION TO FACILITATE AWAKE FIBREOPTIC NASOTRACHEAL INTUBATION.
Journal Title: IJSR-International Journal Of Scientific Research - Year 2018, Vol 7, Issue 7
Abstract
Awake fiberoptic intubation (AFOI) is the most valuable technique in the management of difficult airway. This study aimed to compare the effectiveness of dexmedetomidine vs propofol infusion in providing conscious sedation during AFOI Method- Sixty eight patients with anticipated difficult intubation posted for elective surgery were enrolled and randomly allocated into the dexmedetomidine (groupA) (0.4mcg/kg bolus infusion over 10 min, followed by0.12mcg/kg/min) (n = 34) or the propofol (groupB)(0.8mg/kg bolus infusion over 10 min, followed by 0.08 mg/kg/min) (n = 34). Endoscopy and intubation conditions, level of sedation amnesia and patient satisfaction as graded by a scoring system were evaluated as the outcomes. Results-Intubation was successful in all patients.There was statistically significant difference in mean endoscopy score (1.71 vs 2.15 ), mean intubation scores for vocal cord movement (1.29 vs 1.68 ) and the mean postintubation scores (1.68 vs 2.21 ) whereas no statistically significant difference was found in mean endoscopy scores for coughing (1.79 vs 2.15 ) and limb movement (1.53 vs1.82 ) The time taken for endoscopy (116.94 seconds vs 124.32 seconds ) and for the intubation (27.21seconds vs27.06 seconds)were similar in two groups .Patients in the propofol group had a significantly higher level of sedation (OAA/S score 2.76vs4.65). Recall of endoscopy and intubation was(gp A vs gpB;82.4% vs 23.5%). There was no statistically significant difference regarding patient satisfaction between the two groups Conclusion. Dexmedetomidine and propofol both were effective for providing conscious sedation during awake fibreoptic nasotracheal intubation.Dexmedetomidine provided better endoscopy and intubation conditions,similar haemodynamic stability without causing any respiratory distress.
Authors and Affiliations
Dr. Poonam Kalra, Dr. Mamta Sharma, Dr. Pramod P, Dr. Shobha Purohit
Keywords
Related Articles
- EP ID EP507813
- DOI -
- Views 51
- Downloads 0
CUSTOMIZED AND COST EFFECTIVE SPECIMEN RETRIEVAL BAG IN LAPAROSCOPIC CHOLECYSTECTOMY: STUDY IN 150 CASES
Minimally invasive surgery has undergone rapid development in last decade and it has many advantages but it has a few drawbacks also like difficulty in removing specimen, spillage of contents intraperitoneally and port s...
A COMPARATIVE STUDY OF COMBINED SPINAL EPIDURAL ANAESTHESIA VERSUS EPIDURAL ANAESTHESIA FOR ELECTIVE CAESAREAN SECTION
Background and aims This study was done to compare the efficacy of combined spinal epidural(CSEA) anaesthesia with epidural anaesthesia based on the parameters such as onset time,quality of intraoperative analgesia, qual...
Electrical and ermal Burns in Jhalawar Region
Developing countries have a high incidence of burn injuries making them an endemic health hazard. High population density, illiteracy and poverty are the main demographic factors associated with high risk of burn injurie...
A STUDY OF ETIOLOGY, ONSET AND TYPE OF NEONATAL SEIZURES
Introduction: A seizure or convulsion is a paroxysmal, time-limited change in motor activity and/or behaviour that results from abnormal electrical activity in the brain. Neonatal seizures are abnormal electrical dischar...
STUDY OF SOME SOCIO-DEMOGRAPHIC FACTORS OF SICKLE CELL DISEASE PATIENTS OF CENTRAL INDIA
Objective: To study some socio- demographic characteristics of sickle cell disease patients from the Vidarbha region of Maharashtra. Methods: This cross-sectional descriptive study was performed at Regional Hemoglobinopa...