The Correlation between Vitamin D and Polycystic Ovary Syndrome
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 70, Issue 7
Abstract
<strong>Background: </strong>A deficiency of Vitamin D not only causes poor bone mineralization but also has been implicated in many other chronic diseases. Recent studies have suggested a relevance of vitamin D to reproductive physiology. Moreover, recent evidence is establishing to support the hypothesis that vitamin D status may contribute to the development of metabolic disturbances in PCOS. <strong>Aim of the Study: To </strong> investigate the relationship between Vitamin D level and polymorphisms related to metabolic disturbances particularly Insulin resistance in women with PCOS. <strong>Methods: </strong>A review of the scientific literature (PubMed Search 1960 to 2017) Pubmed, Embase and CENTRAL were searched to identify randomized controlled trials that investigated The Correlation between Depression and Folate Deficiency as the primary outcome. Identification of papers and data extraction were performed by two independent researchers. We searched for relevant trials in the Cochrane Library, MEDLINE (from 1960), Embase (from 1960), and ongoing trial databases; all searches current to October 2017. <strong>Results: </strong>Eight studies were included enrolling 1225 women; 779 patients with depression and 446 control subjects. Univariate regression analyses of the weighted means indicated a significant correlation between vitamin D and IR predictability in both PCOS and control women. However, the significance was neutralized after factoring BMI in PCOS women. <strong>Conclusion: </strong>There is a growing body of evidence suggesting an inverse association between vitamin D status and metabolic disturbances in PCOS in the current literature yet heterogeneity of the conducted studies made it difficult to come out with a solid conclusion. Nevertheless, normalization of vitamin D levels is recommended generally and especially for PCOS patients. <strong> </strong>
Authors and Affiliations
Eman Helal
Keywords
Related Articles
- EP ID EP583628
- DOI 10.12816/0044540
- Views 123
- Downloads 0
Value of Broncho-Alveolar Lavage in Diagnosis of Newly Developed Lung Infiltrates in Mechanically Ventilated Patients
<strong>Background and Objectives: </strong>in a developing country, cost effectiveness is an important consideration. The aim of this study was to investigate the efficiency and safety of mini broncho-alveolar lavage (m...
Comparative Study between Femoral Arterial Doppler and Echocardiography in fluid responsiveness assessment in Septic Shock Patients
<strong>Background: </strong>Fluid replacement is considered the cornerstone of resuscitation in critically ill patients especially in patients with septic shock. However, only about 50% of critically ill hemodynamically...
Role of Computed Tomography Perfusion Compared to Computed Tomography Triphasic Study in Assessment of Hepatic Focal Lesions
<span>Purpose </span><span>of this study is: to evaluate the role of computed tomography perfusion and computed tomography triphasic in assessment of hepatic focal lesions.<br /> </span><span>Methods: </span><span>The st...
Knowledge, Attitudes and Practice of Nurses in Renal Dialysis Units Regarding Infection Control in Abha City – Saudi Arabia, 2015
Background: patients on hemodialysis are at risk of nosocomial infections especially Hepatitis C Virus (HCV) and Hepatitis B Virus (HBV). Nurses’ adherence to infection control procedures is instrumental to control the t...
Anal Abscesses and Different Methods of its Surgical Management
<strong>Background and Objectives: </strong>in this review wed discuss background of anal abscess and fistula, as well focused on different surgical approaches for dealing with anal abscess, their effectiveness and diffi...