The course and outcome of pregnancy in patient with concomitant Gilbert syndrome and hereditary spherocytosis: a unique case report
Journal Title: Clinical and Experimental Obstetrics & Gynecology - Year 2019, Vol 46, Issue 2
Abstract
Gilbert syndrome (GS) is an autosomal dominant mild unconjugated hyperbilirubinemia. Hereditary spherocytosis (HS) is an inherited condition of non-immune heterogeneous hemolytic anemia. These two diseases can be very rarely diagnosed in one patient, but there is not one case reported in pregnant patient. The authors present a unique case of concomitant both diseases in pregnancy. The patient was 25- years-old, conceived spontaneously, and carefully observed throughout the pregnancy. Considering that both diseases might have a detrimental influence on pregnancy course and outcome, especially in this case with severe form of HS, the woman was hospitalized and carefully observed until the end of pregnancy. She delivered vaginally without any feto-maternal complications. In conclusion, coexisting GS and HS during pregnancy deserve careful monitoring and up-to-date treatment. This case report shows that a contemporary approach to the pregnant patient with GS and HS can result in the delivery of a healthy baby without any complications.
Authors and Affiliations
G. Bapayeva, M. Terzic, K. Togyzbayeva, A. Bekenova, S. Terzic
Keywords
Related Articles
- EP ID EP620265
- DOI 10.12891/ceog4599.2019
- Views 55
- Downloads 0
Plasma urotensin-2 as a marker for menstrual irregularities in women: a clinical study
Purpose of Investigation: The objectives of this study were to evaluate urotensin 2 (UT-2) serum levels, a potent vasoconstrictor, in women with irregular menstrual irregularities and to determine its course in irregular...
Quantitative detection of cell-free fetal DNA in peripheral blood of pregnant women during early pregnancy
Objective: This study aimed for the quantitative detection of cell-free fetal DNA (cffDNA) in peripheral plasma of pregnant women, which provides basic data for clinical non-invasive prenatal screening in early pregnancy...
Term pregnancy not requiring cerclage placement or tocolytic therapy in a patient with a unicornuate uterus and history of myomectomy
The authors present the case of a 28-year-old nulliparous woman, who successfully carried a term pregnancy in a unicornuate uterus with a solid non-communicating rudimentary horn, and a history of myomectomy, without cer...
Myomectomy over the age of forty
Purpose of investigation: The aim of this study is to evaluate the fertility results of women who had myomectomy surgery in their forties for fertility preservation. Materials and Methods: All women who had myomectomy su...
Downregulation of Hsp27 inhibits proliferation, migration and invasion in human choriocarcinoma cell line JAR
Purpose of Investigation: Heat shock protein 27 (Hsp27), a member of the heat shock protein (Hsp) family, is critical in the stress response. However, the role of Hsp27 in the pathogenesis of preeclampsia remains unknown...